A gestational profile of placental exosomes in maternal plasma and their effects on endothelial cell migration

• Published in: PloS one Vol. 9; no. 6; p. e98667
• Main Authors: Salomon, Carlos, Torres, Maria Jose, Kobayashi, Miharu, Scholz-Romero, Katherin, Sobrevia, Luis, Dobierzewska, Aneta, Illanes, Sebastian E, Mitchell, Murray D, Rice, Gregory E
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 06.06.2014; Public Library of Science (PLoS)
• Subjects: Adult; Biological activity; Biology and Life Sciences; Biomarkers - metabolism; Cancer; CD63 antigen; Cell interactions; Cell migration; Cell Movement; Cell signaling; Diabetes; Endothelial cells; Endothelial Cells - cytology; Endothelium; Exosomes; Exosomes - metabolism; Female; Fetuses; Gestational Age; Gynecology; Humans; Laboratories; Lipids; Male; Medicine; Medicine and Health Sciences; Mothers; Obstetrics; Physiology; Placenta; Placenta - cytology; Plasma; Plasma - cytology; Pregnancy; Pregnant women; Womens health; Queensland Australia; Australia

Studies completed to date provide persuasive evidence that placental cell-derived exosomes play a significant role in intercellular communication pathways that potentially contribute to placentation and development of materno-fetal vascular circulation. The aim of this study was to establish the ges...