Health status and risk profiles for brain aging of rural‐dwelling older adults: Data from the interdisciplinary baseline assessments in MIND‐China
Introduction Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment approaches, health conditions, and risk profiles for brain aging of participants in the randomized controlled Multimodal INterventions to delay...
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| Published in | Alzheimer's & dementia : translational research & clinical interventions Vol. 8; no. 1; pp. e12254 - n/a |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
John Wiley & Sons, Inc
2022
John Wiley and Sons Inc Wiley |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Introduction
Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment approaches, health conditions, and risk profiles for brain aging of participants in the randomized controlled Multimodal INterventions to delay Dementia and disability in rural China (MIND‐China).
Methods
MIND‐China engaged residents who were ≥60 years of age and living in rural communities in the western Shandong province. In March to September 2018, all participants underwent the core module assessments via face‐to‐face interviews, clinical examinations, neuropsychological testings, and laboratory tests. Specific modules of examination were performed for sub‐samples, including brain magnetic resonance imaging scans, genetic and blood biochemical markers, actigraphy testing, cardiopulmonary coupling analysis for sleep quality and disturbances, audiometric testing, and optical coherence tomography examination. We performed descriptive analysis.
Results
In total, 5765 participants (74.9% of all eligible residents) undertook the baseline assessments. The mean age was 70.9 years (standard deviation, 5.9), 57.2% were women, 40.6% were illiterate, and 88.3% were farmers. The overall prevalence of common chronic diseases was 67.2% for hypertension, 23.4% for dyslipidemia, 23.5% for heart disease, 14.4% for diabetes mellitus, and 5.4% for dementia. The prevalence rates of hypertension, diabetes mellitus, dyslipidemia, obesity, heart disease, depressive symptoms, and dementia were higher in women than in men (P < .05). Overall, 87.1% of the participants had at least two of the 15 chronic diseases (89.3% in women vs 84.2% in men, P < .001). Participants examined for the specific modules were younger, more likely to be women, and more educated than those not examined.
Discussion
Comprehensive baseline assessments of participants in MIND‐China provide extremely valuable data sources for interdisciplinary research into the complex relationships of aging, health, brain aging, and functional consequences among older adults living in the rural communities.
Highlights
MIND‐China is a multimodal intervention study among rural residents ≥60 years of age.
At baseline, 5765 participants undertook the interdisciplinary assessments.
The baseline assessments consisted of core module and specific modules.
Specific modules included brain magnetic resonance imaging (MRI), blood biomarkers, ActiGraph, cardiopulmonary coupling (CPC), pure‐tone audiometry (PTA), and optical coherence tomography (OCT). |
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| AbstractList | Abstract
Introduction
Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment approaches, health conditions, and risk profiles for brain aging of participants in the randomized controlled Multimodal INterventions to delay Dementia and disability in rural China (MIND‐China).
Methods
MIND‐China engaged residents who were ≥60 years of age and living in rural communities in the western Shandong province. In March to September 2018, all participants underwent the core module assessments via face‐to‐face interviews, clinical examinations, neuropsychological testings, and laboratory tests. Specific modules of examination were performed for sub‐samples, including brain magnetic resonance imaging scans, genetic and blood biochemical markers, actigraphy testing, cardiopulmonary coupling analysis for sleep quality and disturbances, audiometric testing, and optical coherence tomography examination. We performed descriptive analysis.
Results
In total, 5765 participants (74.9% of all eligible residents) undertook the baseline assessments. The mean age was 70.9 years (standard deviation, 5.9), 57.2% were women, 40.6% were illiterate, and 88.3% were farmers. The overall prevalence of common chronic diseases was 67.2% for hypertension, 23.4% for dyslipidemia, 23.5% for heart disease, 14.4% for diabetes mellitus, and 5.4% for dementia. The prevalence rates of hypertension, diabetes mellitus, dyslipidemia, obesity, heart disease, depressive symptoms, and dementia were higher in women than in men (
P
< .05). Overall, 87.1% of the participants had at least two of the 15 chronic diseases (89.3% in women vs 84.2% in men,
P
< .001). Participants examined for the specific modules were younger, more likely to be women, and more educated than those not examined.
Discussion
Comprehensive baseline assessments of participants in MIND‐China provide extremely valuable data sources for interdisciplinary research into the complex relationships of aging, health, brain aging, and functional consequences among older adults living in the rural communities.
Highlights
MIND‐China is a multimodal intervention study among rural residents ≥60 years of age.
At baseline, 5765 participants undertook the interdisciplinary assessments.
The baseline assessments consisted of core module and specific modules.
Specific modules included brain magnetic resonance imaging (MRI), blood biomarkers, ActiGraph, cardiopulmonary coupling (CPC), pure‐tone audiometry (PTA), and optical coherence tomography (OCT). Introduction : Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment approaches, health conditions, and risk profiles for brain aging of participants in the randomized controlled Multimodal INterventions to delay Dementia and disability in rural China (MIND-China). Methods : MIND-China engaged residents who were >= 60 years of age and living in rural communities in the western Shandong province. In March to September 2018, all participants underwent the core module assessments via face-to-face interviews, clinical examinations, neuropsychological testings, and laboratory tests. Specific modules of examination were performed for sub-samples, including brain magnetic resonance imaging scans, genetic and blood biochemical markers, actigraphy testing, cardiopulmonary coupling analysis for sleep quality and disturbances, audiometric testing, and optical coherence tomography examination. We performed descriptive analysis. Results : In total, 5765 participants (74.9% of all eligible residents) undertook the baseline assessments. The mean age was 70.9 years (standard deviation, 5.9), 57.2% were women, 40.6% were illiterate, and 88.3% were farmers. The overall prevalence of common chronic diseases was 67.2% for hypertension, 23.4% for dyslipidemia, 23.5% for heart disease, 14.4% for diabetes mellitus, and 5.4% for dementia. The prevalence rates of hypertension, diabetes mellitus, dyslipidemia, obesity, heart disease, depressive symptoms, and dementia were higher in women than in men (P < .05). Overall, 87.1% of the participants had at least two of the 15 chronic diseases (89.3% in women vs 84.2% in men, P < .001). Participants examined for the specific modules were younger, more likely to be women, and more educated than those not examined. Discussion : Comprehensive baseline assessments of participants in MIND-China provide extremely valuable data sources for interdisciplinary research into the complex relationships of aging, health, brain aging, and functional consequences among older adults living in the rural communities. Highlights MIND-China is a multimodal intervention study among rural residents >= 60 years of age. At baseline, 5765 participants undertook the interdisciplinary assessments. The baseline assessments consisted of core module and specific modules. Specific modules included brain magnetic resonance imaging (MRI), blood biomarkers, ActiGraph, cardiopulmonary coupling (CPC), pure-tone audiometry (PTA), and optical coherence tomography (OCT). Introduction : Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment approaches, health conditions, and risk profiles for brain aging of participants in the randomized controlled Multimodal INterventions to delay Dementia and disability in rural China (MIND-China). Methods : MIND-China engaged residents who were >= 60 years of age and living in rural communities in the western Shandong province. In March to September 2018, all participants underwent the core module assessments via face-to-face interviews, clinical examinations, neuropsychological testings, and laboratory tests. Specific modules of examination were performed for sub-samples, including brain magnetic resonance imaging scans, genetic and blood biochemical markers, actigraphy testing, cardiopulmonary coupling analysis for sleep quality and disturbances, audiometric testing, and optical coherence tomography examination. We performed descriptive analysis. Results : In total, 5765 participants (74.9% of all eligible residents) undertook the baseline assessments. The mean age was 70.9 years (standard deviation, 5.9), 57.2% were women, 40.6% were illiterate, and 88.3% were farmers. The overall prevalence of common chronic diseases was 67.2% for hypertension, 23.4% for dyslipidemia, 23.5% for heart disease, 14.4% for diabetes mellitus, and 5.4% for dementia. The prevalence rates of hypertension, diabetes mellitus, dyslipidemia, obesity, heart disease, depressive symptoms, and dementia were higher in women than in men (P < .05). Overall, 87.1% of the participants had at least two of the 15 chronic diseases (89.3% in women vs 84.2% in men, P < .001). Participants examined for the specific modules were younger, more likely to be women, and more educated than those not examined. Discussion : Comprehensive baseline assessments of participants in MIND-China provide extremely valuable data sources for interdisciplinary research into the complex relationships of aging, health, brain aging, and functional consequences among older adults living in the rural communities. Highlights : MIND-China is a multimodal intervention study among rural residents >= 60 years of age. At baseline, 5765 participants undertook the interdisciplinary assessments. The baseline assessments consisted of core module and specific modules. Specific modules included brain magnetic resonance imaging (MRI), blood biomarkers, ActiGraph, cardiopulmonary coupling (CPC), pure-tone audiometry (PTA), and optical coherence tomography (OCT). Introduction Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment approaches, health conditions, and risk profiles for brain aging of participants in the randomized controlled Multimodal INterventions to delay Dementia and disability in rural China (MIND‐China). Methods MIND‐China engaged residents who were ≥60 years of age and living in rural communities in the western Shandong province. In March to September 2018, all participants underwent the core module assessments via face‐to‐face interviews, clinical examinations, neuropsychological testings, and laboratory tests. Specific modules of examination were performed for sub‐samples, including brain magnetic resonance imaging scans, genetic and blood biochemical markers, actigraphy testing, cardiopulmonary coupling analysis for sleep quality and disturbances, audiometric testing, and optical coherence tomography examination. We performed descriptive analysis. Results In total, 5765 participants (74.9% of all eligible residents) undertook the baseline assessments. The mean age was 70.9 years (standard deviation, 5.9), 57.2% were women, 40.6% were illiterate, and 88.3% were farmers. The overall prevalence of common chronic diseases was 67.2% for hypertension, 23.4% for dyslipidemia, 23.5% for heart disease, 14.4% for diabetes mellitus, and 5.4% for dementia. The prevalence rates of hypertension, diabetes mellitus, dyslipidemia, obesity, heart disease, depressive symptoms, and dementia were higher in women than in men (P < .05). Overall, 87.1% of the participants had at least two of the 15 chronic diseases (89.3% in women vs 84.2% in men, P < .001). Participants examined for the specific modules were younger, more likely to be women, and more educated than those not examined. Discussion Comprehensive baseline assessments of participants in MIND‐China provide extremely valuable data sources for interdisciplinary research into the complex relationships of aging, health, brain aging, and functional consequences among older adults living in the rural communities. Highlights MIND‐China is a multimodal intervention study among rural residents ≥60 years of age. At baseline, 5765 participants undertook the interdisciplinary assessments. The baseline assessments consisted of core module and specific modules. Specific modules included brain magnetic resonance imaging (MRI), blood biomarkers, ActiGraph, cardiopulmonary coupling (CPC), pure‐tone audiometry (PTA), and optical coherence tomography (OCT). Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment approaches, health conditions, and risk profiles for brain aging of participants in the randomized controlled Multimodal INterventions to delay Dementia and disability in rural China (MIND-China). MIND-China engaged residents who were ≥60 years of age and living in rural communities in the western Shandong province. In March to September 2018, all participants underwent the core module assessments via face-to-face interviews, clinical examinations, neuropsychological testings, and laboratory tests. Specific modules of examination were performed for sub-samples, including brain magnetic resonance imaging scans, genetic and blood biochemical markers, actigraphy testing, cardiopulmonary coupling analysis for sleep quality and disturbances, audiometric testing, and optical coherence tomography examination. We performed descriptive analysis. In total, 5765 participants (74.9% of all eligible residents) undertook the baseline assessments. The mean age was 70.9 years (standard deviation, 5.9), 57.2% were women, 40.6% were illiterate, and 88.3% were farmers. The overall prevalence of common chronic diseases was 67.2% for hypertension, 23.4% for dyslipidemia, 23.5% for heart disease, 14.4% for diabetes mellitus, and 5.4% for dementia. The prevalence rates of hypertension, diabetes mellitus, dyslipidemia, obesity, heart disease, depressive symptoms, and dementia were higher in women than in men ( < .05). Overall, 87.1% of the participants had at least two of the 15 chronic diseases (89.3% in women vs 84.2% in men, < .001). Participants examined for the specific modules were younger, more likely to be women, and more educated than those not examined. Comprehensive baseline assessments of participants in MIND-China provide extremely valuable data sources for interdisciplinary research into the complex relationships of aging, health, brain aging, and functional consequences among older adults living in the rural communities. MIND-China is a multimodal intervention study among rural residents ≥60 years of age.At baseline, 5765 participants undertook the interdisciplinary assessments.The baseline assessments consisted of core module and specific modules.Specific modules included brain magnetic resonance imaging (MRI), blood biomarkers, ActiGraph, cardiopulmonary coupling (CPC), pure-tone audiometry (PTA), and optical coherence tomography (OCT). Abstract Introduction Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment approaches, health conditions, and risk profiles for brain aging of participants in the randomized controlled Multimodal INterventions to delay Dementia and disability in rural China (MIND‐China). Methods MIND‐China engaged residents who were ≥60 years of age and living in rural communities in the western Shandong province. In March to September 2018, all participants underwent the core module assessments via face‐to‐face interviews, clinical examinations, neuropsychological testings, and laboratory tests. Specific modules of examination were performed for sub‐samples, including brain magnetic resonance imaging scans, genetic and blood biochemical markers, actigraphy testing, cardiopulmonary coupling analysis for sleep quality and disturbances, audiometric testing, and optical coherence tomography examination. We performed descriptive analysis. Results In total, 5765 participants (74.9% of all eligible residents) undertook the baseline assessments. The mean age was 70.9 years (standard deviation, 5.9), 57.2% were women, 40.6% were illiterate, and 88.3% were farmers. The overall prevalence of common chronic diseases was 67.2% for hypertension, 23.4% for dyslipidemia, 23.5% for heart disease, 14.4% for diabetes mellitus, and 5.4% for dementia. The prevalence rates of hypertension, diabetes mellitus, dyslipidemia, obesity, heart disease, depressive symptoms, and dementia were higher in women than in men (P < .05). Overall, 87.1% of the participants had at least two of the 15 chronic diseases (89.3% in women vs 84.2% in men, P < .001). Participants examined for the specific modules were younger, more likely to be women, and more educated than those not examined. Discussion Comprehensive baseline assessments of participants in MIND‐China provide extremely valuable data sources for interdisciplinary research into the complex relationships of aging, health, brain aging, and functional consequences among older adults living in the rural communities. Highlights MIND‐China is a multimodal intervention study among rural residents ≥60 years of age. At baseline, 5765 participants undertook the interdisciplinary assessments. The baseline assessments consisted of core module and specific modules. Specific modules included brain magnetic resonance imaging (MRI), blood biomarkers, ActiGraph, cardiopulmonary coupling (CPC), pure‐tone audiometry (PTA), and optical coherence tomography (OCT). IntroductionMultidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment approaches, health conditions, and risk profiles for brain aging of participants in the randomized controlled Multimodal INterventions to delay Dementia and disability in rural China (MIND-China).MethodsMIND-China engaged residents who were ≥60 years of age and living in rural communities in the western Shandong province. In March to September 2018, all participants underwent the core module assessments via face-to-face interviews, clinical examinations, neuropsychological testings, and laboratory tests. Specific modules of examination were performed for sub-samples, including brain magnetic resonance imaging scans, genetic and blood biochemical markers, actigraphy testing, cardiopulmonary coupling analysis for sleep quality and disturbances, audiometric testing, and optical coherence tomography examination. We performed descriptive analysis.ResultsIn total, 5765 participants (74.9% of all eligible residents) undertook the baseline assessments. The mean age was 70.9 years (standard deviation, 5.9), 57.2% were women, 40.6% were illiterate, and 88.3% were farmers. The overall prevalence of common chronic diseases was 67.2% for hypertension, 23.4% for dyslipidemia, 23.5% for heart disease, 14.4% for diabetes mellitus, and 5.4% for dementia. The prevalence rates of hypertension, diabetes mellitus, dyslipidemia, obesity, heart disease, depressive symptoms, and dementia were higher in women than in men (P < .05). Overall, 87.1% of the participants had at least two of the 15 chronic diseases (89.3% in women vs 84.2% in men, P < .001). Participants examined for the specific modules were younger, more likely to be women, and more educated than those not examined.DiscussionComprehensive baseline assessments of participants in MIND-China provide extremely valuable data sources for interdisciplinary research into the complex relationships of aging, health, brain aging, and functional consequences among older adults living in the rural communities.HighlightsMIND-China is a multimodal intervention study among rural residents ≥60 years of age.At baseline, 5765 participants undertook the interdisciplinary assessments.The baseline assessments consisted of core module and specific modules.Specific modules included brain magnetic resonance imaging (MRI), blood biomarkers, ActiGraph, cardiopulmonary coupling (CPC), pure-tone audiometry (PTA), and optical coherence tomography (OCT). |
| Author | Wang, Yongxiang Fratiglioni, Laura Yin, Ling Kivipelto, Miia Feng, Jianli Jia, Jianping Li, Yuanjing Liu, Cuicui Dong, Yi Liu, Rui Song, Lin Du, Yifeng Han, Xiaolei Persson, Jonas Zhang, Qinghua Hou, Tingting Han, Xiaojuan Tang, Shi Launer, Lenore J Zhang, Xianda Cong, Lin Carrillo, Maria Zhang, Zhonglin Ngandu, Tiia Qiu, Chengxuan Snyder, Heather |
| AuthorAffiliation | 5 Department of Neurology Shandong Second Provincial General Hospital Shandong Provincial ENT Hospital Jinan Shandong China 3 Shandong Provincial Clinical Research Center for Neurological Diseases Jinan Shandong China 11 Innovation Center for Neurological Disorders Department of Neurology Xuanwu Hospital Capital Medical University Beijing China 9 Aging Research Center Department of NVS Karolinska Institutet and Stockholm University Stockholm Sweden 7 Department of Public Health and Welfare Finnish Institute for Health and Welfare Finland 2 Department of Neurology Shandong Provincial Hospital Cheeloo College of Medicine Shandong University Jinan Shandong China 6 Division of Clinical Geriatrics and Center for Alzheimer Research Department of Neurobiology Care Sciences and Society (NVS) Karolinska Institutet Stockholm Sweden 4 Yanlou Town Hospital Yanggu Shandong China 1 Department of Neurology Shandong Provincial Hospital affiliated to Shandong First Medical University Jinan Shandong China 8 Alzh |
| AuthorAffiliation_xml | – name: 7 Department of Public Health and Welfare Finnish Institute for Health and Welfare Finland – name: 10 Intramural Research Program Laboratory of Epidemiology and Population Sciences National Institute on Aging National Institutes of Health Baltimore Maryland USA – name: 8 Alzheimer's Association Chicago Illinois USA – name: 3 Shandong Provincial Clinical Research Center for Neurological Diseases Jinan Shandong China – name: 2 Department of Neurology Shandong Provincial Hospital Cheeloo College of Medicine Shandong University Jinan Shandong China – name: 1 Department of Neurology Shandong Provincial Hospital affiliated to Shandong First Medical University Jinan Shandong China – name: 5 Department of Neurology Shandong Second Provincial General Hospital Shandong Provincial ENT Hospital Jinan Shandong China – name: 9 Aging Research Center Department of NVS Karolinska Institutet and Stockholm University Stockholm Sweden – name: 6 Division of Clinical Geriatrics and Center for Alzheimer Research Department of Neurobiology Care Sciences and Society (NVS) Karolinska Institutet Stockholm Sweden – name: 11 Innovation Center for Neurological Disorders Department of Neurology Xuanwu Hospital Capital Medical University Beijing China – name: 4 Yanlou Town Hospital Yanggu Shandong China |
| Author_xml | – sequence: 1 givenname: Yongxiang surname: Wang fullname: Wang, Yongxiang organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 2 givenname: Xiaolei surname: Han fullname: Han, Xiaolei organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 3 givenname: Xianda surname: Zhang fullname: Zhang, Xianda organization: Yanlou Town Hospital – sequence: 4 givenname: Zhonglin surname: Zhang fullname: Zhang, Zhonglin organization: Yanlou Town Hospital – sequence: 5 givenname: Lin surname: Cong fullname: Cong, Lin organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 6 givenname: Shi surname: Tang fullname: Tang, Shi organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 7 givenname: Tingting surname: Hou fullname: Hou, Tingting organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 8 givenname: Cuicui surname: Liu fullname: Liu, Cuicui organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 9 givenname: Xiaojuan surname: Han fullname: Han, Xiaojuan organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 10 givenname: Qinghua surname: Zhang fullname: Zhang, Qinghua organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 11 givenname: Jianli surname: Feng fullname: Feng, Jianli organization: Shandong Provincial ENT Hospital – sequence: 12 givenname: Ling surname: Yin fullname: Yin, Ling organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 13 givenname: Lin surname: Song fullname: Song, Lin organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 14 givenname: Yi surname: Dong fullname: Dong, Yi organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 15 givenname: Rui surname: Liu fullname: Liu, Rui organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 16 givenname: Yuanjing surname: Li fullname: Li, Yuanjing organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 17 givenname: Tiia surname: Ngandu fullname: Ngandu, Tiia organization: Finnish Institute for Health and Welfare – sequence: 18 givenname: Miia surname: Kivipelto fullname: Kivipelto, Miia organization: Karolinska Institutet – sequence: 19 givenname: Heather surname: Snyder fullname: Snyder, Heather organization: Alzheimer's Association – sequence: 20 givenname: Maria surname: Carrillo fullname: Carrillo, Maria organization: Alzheimer's Association – sequence: 21 givenname: Jonas surname: Persson fullname: Persson, Jonas organization: Karolinska Institutet and Stockholm University – sequence: 22 givenname: Laura surname: Fratiglioni fullname: Fratiglioni, Laura organization: Karolinska Institutet and Stockholm University – sequence: 23 givenname: Lenore J surname: Launer fullname: Launer, Lenore J organization: National Institutes of Health – sequence: 24 givenname: Jianping surname: Jia fullname: Jia, Jianping organization: Capital Medical University – sequence: 25 givenname: Yifeng orcidid: 0000-0002-4672-6654 surname: Du fullname: Du, Yifeng email: duyifeng@email.sdu.edu.cn organization: Shandong Provincial Clinical Research Center for Neurological Diseases – sequence: 26 givenname: Chengxuan surname: Qiu fullname: Qiu, Chengxuan email: chengxuan.qiu@ki.se organization: Karolinska Institutet and Stockholm University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35441085$$D View this record in MEDLINE/PubMed https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-98714$$DView record from Swedish Publication Index https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-204566$$DView record from Swedish Publication Index http://kipublications.ki.se/Default.aspx?queryparsed=id:235441085$$DView record from Swedish Publication Index |
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| ContentType | Journal Article |
| Copyright | 2022 The Authors. published by Wiley Periodicals, LLC on behalf of Alzheimer's Association 2022 The Authors. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals, LLC on behalf of Alzheimer's Association. 2022. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: 2022 The Authors. published by Wiley Periodicals, LLC on behalf of Alzheimer's Association – notice: 2022 The Authors. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals, LLC on behalf of Alzheimer's Association. – notice: 2022. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
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| DOI | 10.1002/trc2.12254 |
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| License | Attribution-NonCommercial-NoDerivs 2022 The Authors. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals, LLC on behalf of Alzheimer's Association. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
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| References | 2019; 7 2015; 12 1993; 8 2021; 21 1990; 55 2019; 4 1991; 14 2019; 31 2019; 11 2020; 143 1993; 43 2015; 385 2016; 388 2020; 17 2020; 16 2020; 14 1994; 49 1994 2018; 62 2020; 12 2008; 30 2020; 11 2020; 10 2011; 14 2011; 7 2019; 365 2016; 12 1989; 28 2017; 95 2010; 67 2021; 13 2020; 5 2000; 15 1997; 32 2017; 16 2017; 13 2018; 115 2015; 198 1995; 43 1999; 131 2018; 90 2011; 66 2020; 26 2014; 13 e_1_2_7_6_1 e_1_2_7_5_1 e_1_2_7_4_1 e_1_2_7_3_1 e_1_2_7_9_1 e_1_2_7_8_1 e_1_2_7_7_1 e_1_2_7_19_1 e_1_2_7_18_1 e_1_2_7_17_1 e_1_2_7_16_1 e_1_2_7_40_1 e_1_2_7_2_1 e_1_2_7_15_1 e_1_2_7_41_1 e_1_2_7_14_1 e_1_2_7_42_1 e_1_2_7_13_1 e_1_2_7_43_1 e_1_2_7_12_1 e_1_2_7_44_1 e_1_2_7_11_1 e_1_2_7_45_1 e_1_2_7_10_1 American Psychiatric Association (e_1_2_7_29_1) 1994 e_1_2_7_26_1 e_1_2_7_27_1 e_1_2_7_28_1 e_1_2_7_30_1 e_1_2_7_25_1 e_1_2_7_31_1 e_1_2_7_24_1 e_1_2_7_32_1 e_1_2_7_23_1 e_1_2_7_33_1 e_1_2_7_22_1 e_1_2_7_34_1 e_1_2_7_35_1 e_1_2_7_20_1 e_1_2_7_36_1 e_1_2_7_37_1 e_1_2_7_38_1 e_1_2_7_39_1 Hu MY (e_1_2_7_21_1) 1997; 32 |
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| Snippet | Introduction
Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment... Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment approaches,... Abstract Introduction Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline... IntroductionMultidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment... Introduction : Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline assessment... Abstract Introduction Multidomain intervention approaches have emerged as a potential strategy to reduce dementia risk. We sought to describe the baseline... |
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| SubjectTerms | Aging Alzheimer's disease Audiometry Brain research Cognitive ability Consent Dementia Diabetes Disease prevention Education Epidemiology Family medical history Hospitals Hypertension Interdisciplinary aspects Intervention Lifestyles Magnetic resonance imaging Medicin och hälsovetenskap Mental disorders Middle age multimodal intervention older adults Older people Population-based studies population-based study Psychology Psykologi Risk factors rural area Rural areas Tomography |
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| Title | Health status and risk profiles for brain aging of rural‐dwelling older adults: Data from the interdisciplinary baseline assessments in MIND‐China |
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