BCL3 exerts an oncogenic function by regulating STAT3 in human cervical cancer

• Published in: OncoTargets and therapy Vol. 9; pp. 6619 - 6629
• Main Authors: Zhao, Hu, Wang, Wuliang, Zhao, Qinghe, Hu, Guiming, Deng, Kehong, Liu, Yuling
• Format: Journal Article
• Language: English
• Published: New Zealand Dove Medical Press Limited 01.01.2016; Taylor & Francis Ltd; Dove Medical Press
• Subjects: Apoptosis; BCL3; Biotechnology; Breast cancer; Cancer therapies; Care and treatment; Cell cycle; Cell growth; Cell proliferation; Cervical cancer; Chemotherapy; Colorectal cancer; Development and progression; Diagnosis; Gene expression; Genetic aspects; Gynecology; Health aspects; Human papillomavirus; Liver cancer; Lymphoma; Medical prognosis; Metastasis; Obstetrics; Oncogenes; Original Research; Ovarian cancer; Proteins; Radiation therapy; STAT3; Xenografts; China; United States > US; B-cell CLL/lymphoma 3; signal transducer and activator of transcription 3; cell proliferation; cell cycle; cervical carcinoma

Aberrant expression of oncogenes and/or tumor suppressors play a fundamental effect on the pathogenesis and tumorigenicity of cervical cancer (CC). B-cell CLL/lymphoma 3 (BCL3) was previously found to be a putative proto-oncogene in human cancers and regulated signal transducer and activator of tran...