Fc-optimized antibodies elicit CD8 immunity to viral respiratory infection - Bournazos, Stylianos; Corti, Davide; Virgin, Herbert W.; Ravetch, Jeffrey V. (Nature (London), 2020)
Keywords: 13/109; 13/31; 45/23; 45/70; 631/154/51/1568; 631/250/251/1567; 631/250/255/2514; 64/110; 64/60; 82/1; 82/103; 82/80; 82/83; Analysis; Animal models; Animals; Antibodies; Antibodies, Monoclonal - chemistry; Antibodies, Monoclonal - immunology; Antibodies, Viral - chemistry; Antibodies, Viral - immunology; Antigen-antibody complexes; Antigens; Binding; CD103 antigen; CD11b antigen; CD11c antigen; CD8 antigen; CD8 lymphocytes; CD8-Positive T-Lymphocytes - cytology; CD8-Positive T-Lymphocytes - immunology; Cdc2 protein; Cell Differentiation; Crosslinking; Dendritic cells; Dendritic Cells - cytology; Dendritic Cells - immunology; Dendritic structure; Domains; Fc receptors; Female; Health aspects; Hemagglutinin Glycoproteins, Influenza Virus - immunology; Human performance; Humanities and Social Sciences; Humans; IgG antibody; Immune response; Immune system; Immunity; Immunoglobulin Fc Fragments - chemistry; Immunoglobulin Fc Fragments - immunology; Immunoglobulin G; Immunoglobulin G - chemistry; Immunoglobulin G - immunology; Infections; Influenza; Influenza, Human - drug therapy; Influenza, Human - immunology; Influenza, Human - mortality; Influenza, Human - prevention & control; Intracellular signalling; Kinases; Leukocytes (neutrophilic); Lymphocyte Activation; Lymphocytes; Macrophages; Mice; Monoclonal antibodies; Monocytes; multidisciplinary; Neuraminidase - immunology; Neutrophils; Nitric-oxide synthase; Orthomyxoviridae - immunology; Pathogens; Pharmacokinetics; Physiological aspects; Prevention; Protein interaction; Receptors, IgG - chemistry; Receptors, IgG - immunology; Respiratory tract infection; Science; Science (multidisciplinary); Serum levels; Syk protein; Tumor necrosis factor; Tyrosine; Viral antibodies; Viral infections; Viral pneumonia; Viruses; United States