Search for New Bioactive Marine Natural Products and Application to Drug Development

• Published in: Chemical & pharmaceutical bulletin Vol. 64; no. 8; pp. 1079 - 1083
• Main Author: Kobayashi, Jun’ichi
• Format: Journal Article
• Language: English
• Published: Japan The Pharmaceutical Society of Japan 2016; Pharmaceutical Society of Japan; Japan Science and Technology Agency
• Subjects: Animal Shells - chemistry; Animals; Bacteria - chemistry; bioactive natural product; Biological Products - chemistry; dinoflagellate; Dinoflagellida - chemistry; Drug Discovery; Fungi - chemistry; marine bacteria; marine sponge; marine-derived fungi; Porifera; tunicate; Urochordata

Natural products are well recognized as an important source of lead compounds in drug development. During the past >30 years, we have discovered >1000 novel bioactive natural products from Okinawan marine organisms (sponges, tunicates, cone shells, etc.) and microorganisms (fungi, bacteria, di...