The effect of neoadjuvant radiation therapy on perioperative outcomes among patients undergoing resection of retroperitoneal sarcomas

• Published in: Surgical oncology Vol. 23; no. 3; pp. 155 - 160
• Main Authors: Nussbaum, Daniel P., Speicher, Paul J., Gulack, Brian C., Ganapathi, Asvin M., Keenan, Jeffrey E., Stinnett, Sandra S., Kirsch, David G., Tyler, Douglas S., Blazer, Dan G.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.09.2014; Elsevier Limited
• Subjects: 30-day outcomes; Aged; Alcohol use; Body mass index; Cardiovascular disease; Classification; Codes; Coronary vessels; Cysts; Diabetes; Female; Heart attacks; Hematology, Oncology and Palliative Medicine; Hemophilia; Humans; Length of Stay; Male; Middle Aged; Morbidity; Mortality; Neoadjuvant; Neoadjuvant Therapy - adverse effects; Operative Time; Outcomes; Postoperative Complications; Postoperative Period; Preoperative; Radiation therapy; Radiotherapy; Radiotherapy, Adjuvant - adverse effects; Retroperitoneal Neoplasms - mortality; Retroperitoneal Neoplasms - radiotherapy; Retroperitoneal Neoplasms - surgery; Retroperitoneal sarcoma; Retrospective Studies; Sarcoma; Sarcoma - mortality; Sarcoma - radiotherapy; Sarcoma - surgery; Sepsis; Short-term outcomes; Surgery; Surgical outcomes; Tobacco; Treatment Outcome; Tumors; Variables; NSQIP; RT; Sarcoma; CPT; EORTC; Neoadjuvant; Radiation therapy; Radiotherapy; 30-day outcomes; Outcomes; ICD-9; RPS; Retroperitoneal sarcoma; Preoperative; Short-term outcomes; Current Procedural Terminology; International Classification of Diseases Ninth Revision; European Organisation for Research and Treatment of Cancer; National Surgical Quality Improvement Program
• ISSN: 0960-7404; 1879-3320; 1879-3320
• DOI: 10.1016/j.suronc.2014.07.001

Neoadjuvant radiation therapy (RT) has several theoretical benefits in the treatment of retroperitoneal sarcoma (RPS), but concerns remain about treatment toxicity and perioperative morbidity. There are limited data regarding its effect on perioperative outcomes, most of which come from small, singl...