Saliency, switching, attention and control: a network model of insula function

• Published in: Brain Structure and Function Vol. 214; no. 5-6; pp. 655 - 667
• Main Authors: Menon, Vinod, Uddin, Lucina Q.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.06.2010; Springer Nature B.V
• Subjects: Animals; Attention; Autonomic nervous system; Biomedical and Life Sciences; Biomedicine; Brain; Brain research; Cell Biology; Cerebral Cortex - anatomy & histology; Cerebral Cortex - physiology; Cognition & reasoning; Cognitive ability; Cortex (cingulate); Cortex (motor); Emotions; Executive Function - physiology; Functional anatomy; Humans; Motor systems; Nerve Net - anatomy & histology; Nerve Net - physiology; Neural Networks, Computer; Neurology; Neurosciences; Review; Short term memory; Social interactions; Structure-function relationships; Functional connectivity; Resting-state fMRI; Brain networks; Anterior insula; Granger causality; Diffusing tensor imaging

The insula is a brain structure implicated in disparate cognitive, affective, and regulatory functions, including interoceptive awareness, emotional responses, and empathic processes. While classically considered a limbic region, recent evidence from network analysis suggests a critical role for the...