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Keywords: 13/44; 14/1; 38/39; 45/41; 45/77; 631/67/1990/291/1621/1915; 692/699/67/1990/291/1621/1915; 82/80; Adenine - analogs & derivatives; Adult; Aged; Base Sequence; Biomedicine; Cancer Research; CD79 Antigens - genetics; Chemotherapy; Female; Humans; Infectious Diseases; letter; Lymphocytes; Lymphoma; Lymphoma, Large B-Cell, Diffuse - drug therapy; Lymphoma, Large B-Cell, Diffuse - genetics; Lymphoma, Large B-Cell, Diffuse - mortality; Male; Metabolic Diseases; Middle Aged; Molecular Medicine; Molecular Sequence Data; Mutation; Myeloid Differentiation Factor 88 - genetics; Neurosciences; Pharmacology; Piperidines; Protein Kinase Inhibitors - pharmacology; Pyrazoles - pharmacology; Pyrimidines - pharmacology; Receptors, Antigen, B-Cell - physiology; Signal transduction; Signal Transduction - drug effects; Tumors