Structural analysis of the GPI glycan

• Published in: PloS one Vol. 16; no. 9; p. e0257435
• Main Authors: Nakano, Miyako, Sabido-Bozo, Susana, Okazaki, Kouta, Aguilera-Romero, Auxiliadora, Rodriguez-Gallardo, Sofia, Cortes-Gomez, Alejandro, Lopez, Sergio, Ikeda, Atsuko, Funato, Kouichi, Muñiz, Manuel
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 16.09.2021; Public Library of Science (PLoS)
• Subjects: Analysis; Biology and Life Sciences; Cell membranes; Cell surface; Electrophoresis; Endoplasmic reticulum; Enzymes; Eukaryotes; Glycan; Glycolipids; Glycosylphosphatidylinositol; Ions; Lab Protocol; Mass spectrometry; Mass spectroscopy; Peptides; Plasma; Polysaccharides; Post-translation; Proteins; Research and Analysis Methods; Scientific imaging; Structural analysis; Structure; Trypsin; Yeast; Yeasts; United States; Japan; Spain

Glycosylphosphatidylinositol (GPI) anchoring of proteins is an essential post-translational modification in all eukaryotes that occurs at the endoplasmic reticulum (ER) and serves to deliver GPI-anchored proteins (GPI-APs) to the cell surface where they play a wide variety of vital physiological rol...