DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia - Oakes, Christopher C; Seifert, Marc; Assenov, Yassen; Gu, Lei; Przekopowitz, Martina; Ruppert, Amy S; Wang, Qi; Imbusch, Charles D; Serva, Andrius; Koser, Sandra D; Brocks, David; Lipka, Daniel B; et al. (Nature genetics, 2016)
Keywords: 13/1; 13/106; 38/91; 45/22; 45/23; 45/90; 631/208/177; 692/699/67/1990/283/1895; Adult; Aged; Aged, 80 and over; Agriculture; Animal Genetics and Genomics; B cells; B-Lymphocytes - immunology; B-Lymphocytes - metabolism; Binding Sites; Biomedicine; Cancer; Cancer Research; Chronic lymphocytic leukemia; Consortia; CpG Islands - genetics; Deoxyribonucleic acid; Development and progression; Developmental stages; DNA; DNA methylation; DNA Methylation - genetics; Epigenesis, Genetic; Epigenetic inheritance; Epigenetics; Female; Gene expression; Gene Expression Regulation, Leukemic; Gene Expression Regulation, Neoplastic; Gene Function; Genetic aspects; Genomes; Growth; Health aspects; Human Genetics; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell - genetics; Leukemia, Lymphocytic, Chronic, B-Cell - immunology; Leukemia, Lymphocytic, Chronic, B-Cell - pathology; Male; Medical research; Middle Aged; Neoplasm Proteins - biosynthesis; Neoplasm Proteins - genetics; Phenotype; Promoter Regions, Genetic; Software; Transcription factors; Tumors