Monitoring HIV Viral Load in Resource Limited Settings: Still a Matter of Debate?

• Published in: PloS one Vol. 7; no. 12; p. e47391
• Main Authors: Arnedo, Mireia, Alonso, Elena, Eisenberg, Nell, Ibáñez, Laura, Ferreyra, Cecilia, Jaén, Angels, Flevaud, Laurence, Khamadi, Samuel, Roddy, Paul, Gatell, Jose Maria, Dalmau, David
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 06.12.2012; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Aged; Anti-HIV Agents - therapeutic use; Antiretroviral agents; Antiretroviral drugs; Antiretroviral Therapy, Highly Active; Antiretrovirals; Biology; Care and treatment; CD4 antigen; CD4 Lymphocyte Count; Developed countries; Drug resistance; Failure; Female; Highly active antiretroviral therapy; HIV; HIV (Viruses); HIV Infections - drug therapy; HIV Infections - virology; HIV patients; HIV Seropositivity - drug therapy; HIV Seropositivity - virology; Human immunodeficiency virus; Humans; Kenya; Lamivudine; Male; Medical research; Medication Adherence; Medicine; Middle Aged; Monitoring; Mutation; Patient compliance; Patients; Protease inhibitors; Rams; Resistència als medicaments; Ribonucleic acid; RNA; Spots; Thymidine; Treatment Outcome; VIH (Virus); Viral Load; Kenya; California; United States > US; Spain

Consequences of lack of viral monitoring in predicting the effects of development of HIV drug resistance mutations during HAART in resource-limited settings (RLS) is still a matter of debate. To assess, among HIV+ patients receiving their first-line HAART, prevalence of virological failure and genot...