Reversal of Apixaban Induced Alterations in Hemostasis by Different Coagulation Factor Concentrates: Significance of Studies In Vitro with Circulating Human Blood - Escolar, Gines; Fernandez-Gallego, Victor; Arellano-Rodrigo, Eduardo; Roquer, Jaume; Reverter, Joan Carles; Sanz, Victoria Veronica; Molina, Patricia; Lopez-Vilchez, Irene; Diaz-Ricart, Maribel; Galan, Ana Maria (PloS one, 2013)
Keywords: Adhesion tests; Alterations; Animals; Anticoagulants; Anticoagulants - pharmacology; Blood; Blood circulation; Blood coagulation; Blood Coagulation - drug effects; Blood platelets; Clinical trials; Clotting; Coagulació sanguínia; Coagulation; Coagulation factors; Damage assessment; Dose-Response Relationship, Drug; Factor VIIa - metabolism; Factor VIIa - pharmacology; Factor Xa - metabolism; Factor Xa Inhibitors; Female; Fibrin; Hemostasis; Hemostatics; Hemostàsia; Hospitals; Humans; Kinetics; Laboratories; Lag phase; Male; Parameter modification; Perfusion; Platelet Adhesiveness - drug effects; Platelets; Prothrombin; Pyrazoles - pharmacology; Pyridones - pharmacology; Rabbits; Reagents; Reversing; Sang; Shear rate; Thrombelastography - methods; Thrombin; Spain