Yeast reveals unexpected roles and regulatory features of aquaporins and aquaglyceroporins

• Published in: Biochimica et biophysica acta Vol. 1840; no. 5; pp. 1482 - 1491
• Main Authors: Ahmadpour, Doryaneh, Geijer, Cecilia, Tamás, Markus J., Lindkvist-Petersson, Karin, Hohmann, Stefan
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2014
• Subjects: Adaptation, Physiological - physiology; adhesion; Amino Acid Sequence; Aquaglyceroporins - chemistry; Aquaglyceroporins - physiology; Aquaporin; aquaporins; Aquaporins - chemistry; Aquaporins - physiology; Basic Medicine; Biologi; Biological Sciences; Cell and Molecular Biology; Cell- och molekylärbiologi; cold tolerance; evolutionary adaptation; Freeze tolerance; Freezing; gene deletion; gene overexpression; genomics; glycerol; lifestyle; MAPK pathway; Medical and Health Sciences; Medicin och hälsovetenskap; Medicinska och farmaceutiska grundvetenskaper; mitogen-activated protein kinase; Molecular Sequence Data; mycology; Osmoregulation; phenotype; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins - physiology; Signal; Signal transduction; spores; Stress resistance; transduction; yeasts; MAPK pathway; Osmoregulation; Signal transduction; Freeze tolerance; Stress resistance; Aquaporin

The yeast Saccharomyces cerevisiae provides unique opportunities to study roles and regulation of aqua/glyceroporins using frontline tools of genetics and genomics as well as molecular cell and systems biology. S. cerevisiae has two similar orthodox aquaporins. Based on phenotypes mediated by gene d...