Comparative Assessment of Cytokine Pattern in Early and Late Onset of Neonatal Sepsis

• Published in: Journal of Immunology Research Vol. 2017; no. 2017; pp. 1 - 8
• Main Authors: Rizvanov, Albert A., Agafonova, E. A., Lombardi, Vincent C., Andreeva, A. A., Anokhin, Vladimir V., Khaiboullina, Svetlana F., Boichuk, S. V., Khaertynov, Kh. S., Satrutdinov, M. A.
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2017; Hindawi; John Wiley & Sons, Inc; Wiley
• Subjects: Acute Disease; Bacteria - immunology; Bacteria - isolation & purification; Bacteria - pathogenicity; Bacterial infections; Biomarkers; Blood; C-Reactive Protein; Comparative analysis; Cytokines; Cytokines - blood; Female; Fungal infections; Fungi - immunology; Fungi - isolation & purification; Fungi - pathogenicity; Health aspects; Humans; Immune response; Immunology; Infant, Newborn; Infants (Newborn); Infection; Inflammation Mediators - blood; Interleukin-10 - blood; Interleukin-6 - blood; Laboratories; Lymphocyte Count; Male; Medical research; Medicine, Experimental; Mortality; Neonatal Sepsis - immunology; Neonatal Sepsis - physiopathology; Neonatal Sepsis - therapy; Newborn babies; Pathogenesis; Sepsis; Statistical analysis; Studies; Tumor necrosis factor; Tumor Necrosis Factor-alpha - blood; Tumor necrosis factor-TNF

Neonatal sepsis is a significant health issue associated with high mortality. Immune responses associated with neonatal sepsis, such as proinflammatory cytokine production, are believed to play a central role in the pathogenesis of this disease. In the present study, serum levels of the proinflammat...