Synthesis and applications of high-performance P-chiral phosphine ligands

• Published in: Proceedings of the Japan Academy, Series B Vol. 97; no. 9; pp. 520 - 542
• Main Author: IMAMOTO, Tsuneo
• Format: Journal Article
• Language: English
• Published: Japan The Japan Academy 11.11.2021
• Subjects: Appointments & personnel changes; asymmetric hydrogenation; Asymmetric synthesis; Asymmetry; Atomic properties; Boron; Catalysis; Catalytic activity; catalytic asymmetric synthesis; Chemical reactions; Chemical synthesis; Enantiomers; enantioselection mechanism; Fluorides; Heavy metals; Hydrogenation; Intermediates; Ligands; Metals; Optical activity; Organic chemistry; P-chiral phosphine ligand; Phosphine; Phosphines; Phosphines - chemistry; phosphine–borane; Phosphorus; Reagents; Review; Rhodium; Transition metals; enantioselection mechanism; P-chiral phosphine ligand; catalytic asymmetric synthesis; asymmetric hydrogenation; phosphine–borane

Metal-catalyzed asymmetric synthesis is one of the most important methods for the economical and environmentally benign production of useful optically active compounds. The success of the asymmetric transformations is significantly dependent on the structure and electronic properties of the chiral l...