A Regulatory Role for NBS1 in Strand-Specific Mutagenesis during Somatic Hypermutation - Du, Likun; Dunn-Walters, Deborah K.; Chrzanowska, Krystyna H.; Stankovic, Tanja; Kotnis, Ashwin; Li, Xin; Lu, Jiayi; Eggertsen, Gösta; Brittain, Claire; Popov, Sergey W.; Gennery, Andrew R.; Taylor, A. Malcolm R.; et al. (PloS one, 2008)
Keywords: Activation-induced cytidine deaminase; Anemia; Ataxia; Ataxia telangiectasia; Ataxia Telangiectasia - genetics; B cells; Base excision repair; Base Sequence; Breakage; Cancer; Cell cycle; Cell Cycle Proteins - genetics; Cell Cycle Proteins - physiology; Cytidine deaminase; Deamination; Deoxyribonucleic acid; DNA; DNA glycosylase; DNA Primers; Endonuclease; Gene mutation; Genes; Humans; Immunoglobulins; Immunology; Immunology/Immune Response; Immunology/Leukocyte Development; In vivo methods and tests; Integrated software; Introns; Laboratories; Lymphocytes B; Medicine; Mismatch repair; MRE11 protein; Mutagenesis; Mutation; Nijmegen breakage syndrome; Nuclear Proteins - genetics; Nuclear Proteins - physiology; Nuclease; Nucleases; Patients; Polymerase Chain Reaction; Pyrimidines; Repair; RNA, Messenger - genetics; Somatic hypermutation; Studies; T cell receptors; Uracil; Uracil-DNA glycosidase