Microstructural and functional gradients are increasingly dissociated in transmodal cortices

• Published in: PLoS biology Vol. 17; no. 5; p. e3000284
• Main Authors: Paquola, Casey, Vos De Wael, Reinder, Wagstyl, Konrad, Bethlehem, Richard A. I., Hong, Seok-Jun, Seidlitz, Jakob, Bullmore, Edward T., Evans, Alan C., Misic, Bratislav, Margulies, Daniel S., Smallwood, Jonathan, Bernhardt, Boris C.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 20.05.2019; Public Library of Science (PLoS)
• Subjects: Adult; Aged; Biology and Life Sciences; Brain; Brain architecture; Cerebral Cortex - anatomy & histology; Cerebral Cortex - physiology; Cognition; Cognitive ability; Cognitive science; Columns (structural); Cortex; Decoding; Decoupling; Differentiation; Female; Functionally gradient materials; Humans; Image reconstruction; Magnetic Resonance Imaging; Male; Medical imaging; Medicine and Health Sciences; Microstructure; Myelin; Neural circuitry; Neuroimaging; Neuroscience; Neurosciences; NMR; Nuclear magnetic resonance; Physical Sciences; Physiological aspects; Psychiatry; Research and Analysis Methods; Social interactions; Software; Structure-function relationships; United Kingdom > UK; Canada; Montreal Quebec Canada

While the role of cortical microstructure in organising neural function is well established, it remains unclear how structural constraints can give rise to more flexible elements of cognition. While nonhuman primate research has demonstrated a close structure-function correspondence, the relationshi...