Wood smoke particles from different combustion phases induce similar pro-inflammatory effects in a co-culture of monocyte and pneumocyte cell lines

• Published in: Particle and fibre toxicology Vol. 9; no. 1; p. 45
• Main Authors: Bølling, Anette Kocbach, Totlandsdal, Annike Irene, Sallsten, Gerd, Braun, Artur, Westerholm, Roger, Bergvall, Christoffer, Boman, Johan, Dahlman, Hans Jørgen, Sehlstedt, Maria, Cassee, Flemming, Sandstrom, Thomas, Schwarze, Per E, Herseth, Jan Inge
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 23.11.2012; BioMed Central; BMC
• Subjects: Air Pollutants - toxicity; Air pollution; Alveolar Epithelial Cells - drug effects; Alveolar Epithelial Cells - immunology; Atoms & subatomic particles; Cell Line; Cell Survival - drug effects; Coculture Techniques; Combustion; Combustion phase; Combustion temperature; Cytokines - metabolism; Emissions; Environmental Health and Occupational Health; Health aspects; Humans; Inflammation; Miljömedicin och yrkesmedicin; Monocytes - drug effects; Monocytes - immunology; Organic Chemicals - analysis; Organic Chemicals - toxicity; Organic fraction; Outdoor air quality; Particulate matter; Particulate Matter - toxicity; Physiological aspects; Polycyclic aromatic hydrocarbons; Risk factors; Smoke - adverse effects; Smoke - analysis; Smoke inhalation injuries; Studies; Wood; Wood smoke; Norway; Sweden

Exposure to particulate matter (PM) has been linked to several adverse cardiopulmonary effects, probably via biological mechanisms involving inflammation. The pro-inflammatory potential of PM depends on the particles' physical and chemical characteristics, which again depend on the emitting sou...