An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway - Robertson, Kevin A.; Hsieh, Wei Yuan; Forster, Thorsten; Blanc, Mathieu; Lu, Hongjin; Crick, Peter J.; Yutuc, Eylan; Watterson, Steven; Martin, Kimberly; Griffiths, Samantha J.; Enright, Anton J.; Yamamoto, Mami; et al. (PLoS biology, 2016)
Keywords: Animals; Binding sites; Biology and life sciences; Biosynthesis; Cholesterol; Cytomegalovirus; Experiments; Gene expression; Infections; Influenza; Interferon; Interferon Regulatory Factor-1 - metabolism; Interferons - physiology; Kinases; Mammals; Mass spectrometry; Metabolism; Metabolites; Methods; Mice, Inbred C57BL; MicroRNA; MicroRNAs; MicroRNAs - metabolism; Physiological aspects; RNA sequencing; Sterols; Sterols - biosynthesis; Viral infections; Virus Diseases - immunology; Viruses