Revisiting the taxonomy and evolution of pathogenicity of the genus Leptospira through the prism of genomics

• Published in: PLoS neglected tropical diseases Vol. 13; no. 5; p. e0007270
• Main Authors: Vincent, Antony T., Schiettekatte, Olivier, Goarant, Cyrille, Neela, Vasantha Kumari, Bernet, Eve, Thibeaux, Roman, Ismail, Nabilah, Mohd Khalid, Mohd Khairul Nizam, Amran, Fairuz, Masuzawa, Toshiyuki, Nakao, Ryo, Amara Korba, Anissa, Bourhy, Pascale, Veyrier, Frederic J., Picardeau, Mathieu
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 23.05.2019; Public Library of Science (PLoS)
• Subjects: Animal health; Animals; Asia; Bacteria; Biodiversity; Biological evolution; Biology; Biology and Life Sciences; Classification; Computer and Information Sciences; Deoxyribonucleic acid; Disease; Disease transmission; DNA; Domains; Evolution; Evolution, Molecular; Evolutionary biology; Genes; Genetic aspects; Genome, Bacterial; Genomes; Genomics; Genotypes; Gram-negative bacteria; Humans; Identification and classification; Laboratories; Leptospira; Leptospira - classification; Leptospira - genetics; Leptospira - isolation & purification; Leptospira - pathogenicity; Leptospirosis; Leptospirosis - microbiology; Life Sciences; Medical research; Medicine and Health Sciences; Microbiological research; Microbiological strains; Microbiology and Parasitology; Natural environment; Novels; Nucleotides; Parasitology; Pathogenicity; Pathogens; Phylogenetics; Phylogeny; Prokaryotes; Saprophytes; Signal transduction; Soil; Soil contamination; Soils; Species classification; Species diversity; Strains; Surface water; Taxonomy; Transmission; Tropical diseases; Urine; Virulence; Virulence (Microbiology); Zoonoses; Zoonoses - microbiology; Asia; France; Canada; United States > US; Japan; Quebec Canada; Kuala Lumpur Malaysia; Malaysia; New Caledonia

The causative agents of leptospirosis are responsible for an emerging zoonotic disease worldwide. One of the major routes of transmission for leptospirosis is the natural environment contaminated with the urine of a wide range of reservoir animals. Soils and surface waters also host a high diversity...