Subscaling of a cytosolic RNA binding protein governs cell size homeostasis in the multiple fission alga Chlamydomonas

• Published in: PLoS genetics Vol. 20; no. 3; p. e1010503
• Main Authors: Liu, Dianyi, Lopez-Paz, Cristina, Li, Yubing, Zhuang, Xiaohong, Umen, James
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 18.03.2024; Public Library of Science (PLoS)
• Subjects: Binding proteins; Biology and Life Sciences; Cell cycle; Cell division; Cell growth; Cell size; Cellular control mechanisms; Chlamydomonas; Cyclin-dependent kinase; Daughters; Diploids; Epistasis; G1 phase; Genetic aspects; Genotype & phenotype; Homeostasis; Kinases; mRNA; Mutation; Physiological aspects; Protein binding; Proteins; Research and Analysis Methods; Retinoblastoma; RNA; RNA-binding protein; Tumor suppressor genes; United States

Coordination of growth and division in eukaryotic cells is essential for populations of proliferating cells to maintain size homeostasis, but the underlying mechanisms that govern cell size have only been investigated in a few taxa. The green alga Chlamydomonas reinhardtii (Chlamydomonas) proliferat...