Probabilistic reversal learning is impaired in Parkinson's disease - Peterson, D.A.; Elliott, C.; Song, D.D.; Makeig, S.; Sejnowski, T.J.; Poizner, H. (Neuroscience, 2009)
Keywords: Adaptation, Psychological; Aged; Aged, 80 and over; Algorithms; basal ganglia; Biological and medical sciences; computational modeling; Computer Simulation; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; dopamine; Feedback, Psychological; Female; Fundamental and applied biological sciences. Psychology; Humans; Learning Disabilities - etiology; Male; Medical sciences; Middle Aged; Models, Psychological; Neurology; Neuropsychological Tests; Parkinson Disease - complications; Primates; Probability Learning; reinforcement learning; Reversal Learning; Reward; Vertebrates: nervous system and sense organs; basal ganglia; PD; BDI; MMSE; UPDRS; computational modeling; dopamine; reinforcement learning; United Parkinson's Disease Rating Scale; Parkinson's disease; Mini-Mental State Exam; Beck Depression Inventory; Nervous system diseases; Dopamine; Central nervous system; Parkinson disease; Basal ganglion; Catecholamine; Encephalon; Cerebral disorder; Learning; Acquisition process; Central nervous system disease; Neurotransmitter; Reinforcement; Degenerative disease; Extrapyramidal syndrome