Unexpected Normal Colloid Osmotic Pressure in Clinical States with Low Serum Albumin

• Published in: PloS one Vol. 11; no. 7; p. e0159839
• Main Authors: Michelis, Regina, Sela, Shifra, Zeitun, Teuta, Geron, Ronit, Kristal, Batya
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 25.07.2016; Public Library of Science (PLoS)
• Subjects: Albumin; Analysis; Apolipoproteins; Biology and Life Sciences; Biomarkers; Chronic kidney failure; Cytokines - metabolism; Dialysis; Fatty acids; Female; Fibrinogen; Gene expression; Hemodialysis; Humans; Hypoalbuminemia - blood; Immunoglobulins; Immunoglobulins - blood; Inflammation; Inflammation Mediators - metabolism; Laboratories; Male; Medicine and Health Sciences; Nephrology; Osmosis; Osmotic Pressure; Oxidation; Oxidation-Reduction; Oxidative Stress; Patients; Physical Sciences; Plasma proteins; Proteins; Proteinuria; Proteinuria - blood; Renal Dialysis; Risk factors; Rodents; Serum Albumin; United States > US; Galilee; Israel

In clinical states associated with systemic oxidative stress (OS) and inflammation such as chronic kidney disease (CKD), oxidative modifications of serum albumin impair its quantification, resulting in apparent hypoalbuminemia. As the maintenance of oncotic pressure/colloid osmotic pressure (COP) is...