Phylogenetic and complementation analysis of a single-stranded DNA binding protein family from lactococcal phages indicates a non-bacterial origin

• Published in: PloS one Vol. 6; no. 11; p. e26942
• Main Authors: Szczepankowska, Agnieszka K, Prestel, Eric, Mariadassou, Mahendra, Bardowski, Jacek K, Bidnenko, Elena
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 04.11.2011; Public Library of Science (PLoS)
• Subjects: Acids; Amino acid sequence; Amino acids; Archaea; Bacteria; Bacteriophages - metabolism; Binding; Biochemistry; Biology; Biophysics; Cladistic analysis; Cloning; Cluster Analysis; Complementation; Datasets; Deoxyribonucleic acid; DNA; DNA biosynthesis; DNA replication; DNA, Single-Stranded - analysis; DNA, Single-Stranded - genetics; E coli; Escherichia coli; Escherichia coli - genetics; Eukaryotes; Evolution; Gene transfer; Genes; Genetic Complementation Test; Genomes; Genomics; Gram-negative bacteria; Laboratories; Lactococcus - virology; Life Sciences; Mutation; Nucleic acids; Phages; Phylogenetics; Phylogeny; Protein binding; Proteins; Single-stranded DNA; Virulence (Microbiology); France; escherichia-coli; identification; gene-transfer

The single-stranded-nucleic acid binding (SSB) protein superfamily includes proteins encoded by different organisms from Bacteria and their phages to Eukaryotes. SSB proteins share common structural characteristics and have been suggested to descend from an ancestor polypeptide. However, as other pr...