Polysaccharide from black currant (Ribes nigrum L.) stimulates dendritic cells through TLR4 signaling

• Published in: Bioscience of Microbiota, Food and Health Vol. 36; no. 4; pp. 141 - 145
• Main Authors: ASHIGAI, Hiroshi, KOMANO, Yuta, WANG, Guanying, KAWACHI, Yasuji, SUNAGA, Kazuko, YAMAMOTO, Reiko, TAKATA, Ryoji, MIYAKE, Mika, YANAI, Takaaki
• Format: Journal Article
• Language: English; Japanese
• Published: Japan BMFH Press 2017; Japan Science and Technology Agency
• Subjects: Anticancer properties; Antitumor activity; black currant; dendritic cell; Dendritic cells; IL-1β; Immunology; immunostimulation; Interleukins; Lymphocytes T; MyD88 protein; polysaccharide; Ribes nigrum; Signaling; TLR4 protein; Toll-like receptors; Tumor necrosis factor-TNF; Tumor necrosis factor-α; black currant; polysaccharide; dendritic cell; immunostimulation

Black currant (Ribes nigrum) has various beneficial properties for human health. In particular, polysaccharide from black currant was found to be an immunostimulating food ingredient and was reported to have antitumor activity in a mouse model. We named it cassis polysaccharide (CAPS). In a previous...