The association between methylphenidate treatment and the risk for fracture among young ADHD patients: A nationwide population-based study in Taiwan

• Published in: PloS one Vol. 12; no. 3; p. e0173762
• Main Authors: Chen, Vincent Chin-Hung, Yang, Yao-Hsu, Liao, Yin-To, Kuo, Ting-Yu, Liang, Hsin-Yi, Huang, Kuo-You, Huang, Yin-Cheng, Lee, Yena, McIntyre, Roger S., Lin, Tzu-Chin
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 15.03.2017; Public Library of Science (PLoS)
• Subjects: Adolescent; Asthma; Attention Deficit Disorder with Hyperactivity - drug therapy; Attention deficit hyperactivity disorder; Biology and Life Sciences; Care and treatment; Child; Child, Preschool; Chinese medicine; Confidence intervals; Diagnosis; Female; Fractures (Injuries); Fractures, Bone - chemically induced; Fractures, Bone - epidemiology; Hazards; Health insurance; Humans; Hyperactivity; Infant; Infant, Newborn; Male; Medical treatment; Medicine and Health Sciences; Methylphenidate; Methylphenidate - adverse effects; Methylphenidate - therapeutic use; Patients; People and Places; Population studies; Population Surveillance; Population-based studies; Retrospective Studies; Risk; Risk factors; Risk reduction; Social Sciences; Statistical models; Studies; Taiwan - epidemiology; Traditional Chinese medicine; Taiwan

Attention-deficit hyperactivity disorder (ADHD) is associated with higher risk for fracture. Whether the medical treatment for ADHD would mitigate the risk remains unclear. In this study, we sought to investigate the effect of methylphenidate treatment on risk for fracture, as well the moderational...