Antipsychotic Medications and Risk of Acute Coronary Syndrome in Schizophrenia: A Nested Case-Control Study

• Published in: PloS one Vol. 11; no. 9; p. e0163533
• Main Authors: Liu, Hsing-Cheng, Yang, Shu-Yu, Liao, Ya-Tang, Chen, Chiao-Chicy, Kuo, Chian-Jue
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 22.09.2016; Public Library of Science (PLoS)
• Subjects: Acute coronary syndromes; Antipsychotic agents; Antipsychotics; Aripiprazole; Bipolar disorder; Chlorpromazine; Coronary heart disease; Drug therapy; Drugs; Haloperidol; Health risk assessment; Medical research; Medicine and Health Sciences; Mental disorders; Mortality; Multiple regression analysis; National health insurance; Online databases; Patients; People and Places; Psychotropic drugs; Regression analysis; Risk assessment; Schizophrenia; Sensitivity; Sensitivity analysis; Therapy; Taiwan

This study assessed the risk of developing acute coronary syndrome requiring hospitalization in association with the use of certain antipsychotic medications in schizophrenia patients. A nationwide cohort of 31,177 inpatients with schizophrenia between the ages of 18 and 65 years whose records were...