Blood Biomarkers of Chronic Inflammation in Gulf War Illness

• Published in: PloS one Vol. 11; no. 6; p. e0157855
• Main Authors: Johnson, Gerhard J., Slater, Billie C. S., Leis, Linda A., Rector, Thomas S., Bach, Ronald R.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 28.06.2016; Public Library of Science (PLoS)
• Subjects: Bioindicators; Biological markers; Biology and Life Sciences; Biomarkers; Biomarkers - blood; Blood; Blood Cell Count; Brain-derived neurotrophic factor; C-reactive protein; C-Reactive Protein - metabolism; Cardiovascular disease; Care and treatment; Case-Control Studies; Chronic fatigue syndrome; Chronic illnesses; Criteria; Data processing; Development and progression; Diagnosis; Diagnostic systems; Etiology; Fatty acids; Female; Fibromyalgia; Government agencies; Gulf War; Gulf War syndrome; Health aspects; Humans; Immunology; Inflammation; Laboratories; Lymphocytes; Male; Medical examination; Medicine; Medicine and Health Sciences; Middle Aged; Military personnel; Monocytes; Neurosciences; Pain; Peripheral blood; Persian Gulf syndrome; Persian Gulf Syndrome - blood; Persian Gulf War; Persian Gulf War veterans; Physiological aspects; Physiology; Plasma proteins; Post traumatic stress disorder; Proteins; Proteome - metabolism; Regression analysis; Serum proteins; Social Sciences; Statistical analysis; Studies; Toxins; Veterans; War; Minnesota; United States > US

More than twenty years following the end of the 1990-1991 Gulf War it is estimated that approximately 300,000 veterans of this conflict suffer from an unexplained chronic, multi-system disorder known as Gulf War Illness (GWI). The etiology of GWI may be exposure to chemical toxins, but it remains on...