A Comprehensive Analysis of miRNA/isomiR Expression with Gender Difference

• Published in: PloS one Vol. 11; no. 5; p. e0154955
• Main Authors: Guo, Li, Liang, Tingming, Yu, Jiafeng, Zou, Quan
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 11.05.2016; Public Library of Science (PLoS)
• Subjects: Analysis; Apoptosis; Autophagy; Bioinformatics; Biology and life sciences; Biophysics; Breast cancer; Cell growth; Datasets; Deregulation; Disease; Disease - genetics; Divergence; Epigenetic inheritance; Female; Females; Gender; Gene expression; Gene Expression Profiling; Gene Expression Regulation; Gene sequencing; Genetic aspects; Genomes; Humans; Laboratories; Loci; Male; Males; Medicine and Health Sciences; MicroRNA; MicroRNAs; MicroRNAs - genetics; MicroRNAs - metabolism; miRNA; Models, Statistical; Physiological aspects; Research and Analysis Methods; Rheumatoid arthritis; Ribonucleic acid; RNA; Sex Characteristics; Sex differences (Biology); Statistical analysis; Statistical methods; Studies; Tissues; Tumors; China

Although microRNAs (miRNAs) have been widely studied as epigenetic regulation molecules, fewer studies focus on the gender difference at the miRNA and isomiR expression levels. In this study, we aim to understand the potential relationships between gender difference and miRNA/isomiR expression throu...