Clinical impact of primary tumor sidedness and sex on unresectable post-recurrence survival in resected pathological stage II-III colorectal cancers: a nationwide multicenter retrospective study

• Published in: BMC Cancer Vol. 22; no. 1; pp. 486 - 10
• Main Authors: Abe, Shinya, Kawai, Kazushige, Nozawa, Hiroaki, Sasaki, Kazuhito, Murono, Koji, Emoto, Shigenobu, Ozawa, Tsuyoshi, Yokoyama, Yuichiro, Nagai, Yuzo, Anzai, Hiroyuki, Sonoda, Hirofumi, Yamauchi, Shinichi, Sugihara, Kenichi, Ishihara, Soichiro
• Format: Journal Article
• Language: English
• Published: England Springer Science and Business Media LLC 02.05.2022; BioMed Central Ltd; BioMed Central; BMC
• Subjects: Adenocarcinoma; Antigens; Cancer therapies; Cecum; Chemoradiotherapy; Chemotherapy; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms; Colorectal Neoplasms - drug therapy; Colorectal Neoplasms - pathology; Colorectal Neoplasms - surgery; Drug therapy; Evaluation; Female; Females; Humans; Liver; Lymph nodes; Lymphatic Metastasis; Lymphatic system; Male; Males; Medical prognosis; Metastases; Metastasis; Mutation; Neoplasm Recurrence, Local; Neoplasm Recurrence, Local - epidemiology; Neoplasm Recurrence, Local - pathology; Neoplasm Staging; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; Outcome; Patients; Peritoneum; Physiological aspects; Primary tumor location; Prognosis; Prognostic marker; Radiation therapy; RC254-282; Retrospective Studies; Review boards; Sex; Sex factors in disease; Surgery; Surveillance; Survival; Tumors; Japan; Primary tumor location; Chemoradiotherapy; Outcome; Prognostic marker; Colorectal cancer

Several studies have demonstrated that right-sided tumors have poorer prognosis than left-sided tumors in patients with unresectable colorectal cancer (CRC). The predictive ability of the tumor sidedness in CRC treated with chemotherapy in each sex is unclear. Subjects were 964 unresectable recurren...