Recursive Cluster Elimination Based Support Vector Machine for Disease State Prediction Using Resting State Functional and Effective Brain Connectivity

• Published in: PloS one Vol. 5; no. 12; p. e14277
• Main Authors: Deshpande, Gopikrishna, Li, Zhihao, Santhanam, Priya, Coles, Claire D., Lynch, Mary Ellen, Hamann, Stephan, Hu, Xiaoping
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 09.12.2010; Public Library of Science (PLoS)
• Subjects: Accuracy; Adolescent; Algorithms; Artificial intelligence; Behavioral sciences; Biomarkers; Biomarkers - metabolism; Biomedical engineering; Brain; Brain - drug effects; Brain - physiology; Brain mapping; Brain Mapping - methods; Brain research; Causality; Child; Classification; Classifiers; Clusters; Cocaine; Cocaine - adverse effects; Cognition; Cognition & reasoning; Cohort Studies; Correlation; Diagnosis; Differential diagnosis; Engineering; Exposure; Female; Functional magnetic resonance imaging; Humans; Hypothesis testing; Localization; Magnetic resonance; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Maternal Exposure; Mathematical models; Mathematics/Statistics; Medical imaging; Neural networks; Neuroimaging; Neurological Disorders/Developmental and Pediatric Neurology; Neurological Disorders/Neuroimaging; Neurological Disorders/Neuropsychiatric Disorders; Neurology; Neuroscience; Neuroscience/Cognitive Neuroscience; Neuroscience/Neurodevelopment; Neuroscience/Psychology; Neurosciences; NMR; Nuclear magnetic resonance; Predictions; Pregnancy; Prenatal experience; Prenatal Exposure Delayed Effects; Preschool children; Radiology and Medical Imaging/Magnetic Resonance Imaging; Reproducibility of Results; Signal processing; Studies; Support vector machines; Trends; Atlanta Georgia; United States > US; Georgia

Brain state classification has been accomplished using features such as voxel intensities, derived from functional magnetic resonance imaging (fMRI) data, as inputs to efficient classifiers such as support vector machines (SVM) and is based on the spatial localization model of brain function. With t...