Solithromycin inhibits IL-13-induced goblet cell hyperplasia and MUC5AC, CLCA1, and ANO1 in human bronchial epithelial cells - Kimura, Yasuhiro; Shinoda, Masahiro; Shinkai, Masaharu; Kaneko, Takeshi (PeerJ, 2023)
Keywords: Acids; Analysis; Anoctamin-1; Anoctamin-1 - genetics; Antibiotics; Asthma; Biology (General); Chloride channel accessory 1; Chloride Channels; Chloride channels (calcium-gated); Chloride Channels - genetics; Drugs and Devices; Epithelial cells; ETS protein; Gene expression; Goblet cell; Goblet Cells; Goblet Cells - drug effects; Goblet Cells - pathology; Humans; Hyperplasia; Interleukin 13; Interleukin-13 - genetics; Interleukins; Kinases; Macrolide antibiotics; Macrolides; Macrolides - pharmacology; Medicine; Microscopy; Molecular modelling; MUC5AC; Mucin; Mucin 5AC; Mucin 5AC - genetics; Mucins; Neoplasm Proteins; Neoplasm Proteins - metabolism; Phosphorylation; Protein expression; Proteins; QH301-705.5; R; Respiratory Medicine; RNA; RNA, Messenger; RNA, Messenger - genetics; SAM pointed domain containing ETS transcription factor; Solithromycin; Stat6 protein; Japan; Goblet cell; Anoctamin-1; Mucin; Solithromycin; SAM pointed domain containing ETS transcription factor; Chloride channel accessory 1; MUC5AC