Spatial Buffering of Light-Evoked Potassium Increases by Retinal Müller (Glial) Cells

• Published in: Science (American Association for the Advancement of Science) Vol. 244; no. 4904; pp. 578 - 580
• Main Authors: Karwoski, Chester J., Lu, Hong-Kai, Newman, Eric A.
• Format: Journal Article
• Language: English
• Published: Washington, DC The American Association for the Advancement of Science 05.05.1989; American Association for the Advancement of Science
• Subjects: Ambystoma; Amphibians; Animals; Barium; Barium - pharmacology; Biochemistry; Bioelectrochemistry; Biological and medical sciences; Electric Conductivity; Electrodes; Eye and associated structures. Visual pathways and centers. Vision; Eyes & eyesight; Fundamental and applied biological sciences. Psychology; Ganglia; Glia; Light; Measurement; Medical research; Modeling; Necturus maculosus; Neuroglia; Neuroglia - drug effects; Neuroglia - metabolism; Neuroglia - radiation effects; Neuroscience; Potassium; Potassium (Chemical element); Potassium - metabolism; Potassium Channels - physiology; Rana pipiens; Retina; Retina - cytology; Simulations; Vertebrates: nervous system and sense organs; Vitreous body; Vitreous Body - metabolism; Frog; Amphibia; Electrophysiology; Luminous stimulus; Retina; Salientia; Muller cell; Ionic current; Inorganic element; Eye; Vertebrata; Light; Potassium

Activity-dependent variations in extracellular potassium concentration in the central nervous system may be regulated, in part, by potassium spatial buffering currents in glial cells. The role of spatial buffering in the retina was assessed by measuring light-evoked potassium changes in amphibian ey...