Impaired hepatic amyloid-beta degradation in Alzheimer’s disease - Maarouf, Chera L.; Walker, Jessica E.; Sue, Lucia I.; Dugger, Brittany N.; Beach, Thomas G.; Serrano, Geidy E. (PloS one, 2018)
Keywords: Aged, 80 and over; Aging; Alzheimer Disease - metabolism; Alzheimer's disease; Amyloid beta-Peptides - chemistry; Amyloid beta-Peptides - metabolism; Amyloid beta-protein; Apolipoprotein E; Biology and Life Sciences; Blood & organ donations; Blood levels; Brain; Brain research; Cathepsin D; Degradation; Dementia; Development and progression; Down syndrome; Enzymes; Female; Fluorescein; Gene expression; Genetic aspects; Genotypes; Humans; Insulin; Insulysin; Liver; Liver - metabolism; Male; Medical research; Medicine and Health Sciences; Neprilysin; Neuropathology; Pathogenesis; Pathology; Peptides; Physiological aspects; Protein Aggregates; Proteins; Proteolysis; Research and Analysis Methods; Studies; Sucrose; Working groups; United States; United States--US; Arizona