An improved method for specific and quantitative determination of the clopidogrel active metabolite isomers in human plasma - Tuffal, Gilles; Roy, Sebastien; Lavisse, Melanie; Brasseur, Denis; Schofield, Joe; Delesque Touchard, Nathalie; Savi, Pierre; Bremond, Nicolas; Rouchon, Marie-Claude; Hurbin, Fabrice; Sultan, Eric (Thrombosis and haemostasis, 2011)
Keywords: Adenosine Diphosphate - analogs & derivatives; Adenosine Diphosphate - chemistry; Adenosine Diphosphate - metabolism; Animals; Blood Platelets - cytology; Blood Platelets - drug effects; Blood Platelets - metabolism; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Humans; Mass Spectrometry; Phosphorus Isotopes - chemistry; Plasma - chemistry; Plasma - cytology; Product Surveillance, Postmarketing - methods; Protein Binding - drug effects; Receptors, Purinergic P2Y12 - genetics; Receptors, Purinergic P2Y12 - metabolism; Sensitivity and Specificity; Stereoisomerism; Thionucleotides - chemistry; Thionucleotides - metabolism; Ticlopidine - analogs & derivatives; Ticlopidine - analysis; Ticlopidine - chemistry; Ticlopidine - pharmacology; Transgenes - genetics