Neuroregeneration and functional recovery after stroke: advancing neural stem cell therapy toward clinical application

Stroke is a main cause of death and disability worldwide. The ability of the brain to self-repair in the acute and chronic phases after stroke is minimal; however, promising stem cell-based interventions are emerging that may give substantial and possibly complete recovery of brain function after st...

Full description

Saved in:
Bibliographic Details
Published inNeural regeneration research Vol. 16; no. 1; pp. 80 - 92
Main Authors Jiao, Yang, Liu, Yu-Wan, Chen, Wei-Gong, Liu, Jing
Format Journal Article
LanguageEnglish
Published India Wolters Kluwer India Pvt. Ltd 01.01.2021
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Stem Cell Clinical Research Center,National Joint Engineering Laboratory,Regenerative Medicine Center,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province,China
Dalian Innovation Institute of Stem Cells and Precision Medicine,Dalian,Liaoning Province,China%Stem Cell Clinical Research Center,National Joint Engineering Laboratory,Regenerative Medicine Center,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province,China
Wolters Kluwer - Medknow
Wolters Kluwer Medknow Publications
Subjects
Brain research
brain; central nervous system; cognitive impairment; neurological function; plasticity; recovery; regeneration; stem cells; stroke
Care and treatment
Nervous system
Neurological research
Patient outcomes
Regeneration
Review
Stem cells
Stroke
Stroke (Disease)
Transplantation
China
stem cells
neurological function
regeneration
plasticity
cognitive impairment
recovery
brain
stroke
central nervous system
Online AccessGet full text

Cover

Abstract Stroke is a main cause of death and disability worldwide. The ability of the brain to self-repair in the acute and chronic phases after stroke is minimal; however, promising stem cell-based interventions are emerging that may give substantial and possibly complete recovery of brain function after stroke. Many animal models and clinical trials have demonstrated that neural stem cells (NSCs) in the central nervous system can orchestrate neurological repair through nerve regeneration, neuron polarization, axon pruning, neurite outgrowth, repair of myelin, and remodeling of the microenvironment and brain networks. Compared with other types of stem cells, NSCs have unique advantages in cell replacement, paracrine action, inflammatory regulation and neuroprotection. Our review summarizes NSC origins, characteristics, therapeutic mechanisms and repair processes, then highlights current research findings and clinical evidence for NSC therapy. These results may be helpful to inform the direction of future stroke research and to guide clinical decision-making.
AbstractList Stroke is a main cause of death and disability worldwide. The ability of the brain to self-repair in the acute and chronic phases after stroke is minimal; however, promising stem cell-based interventions are emerging that may give substantial and possibly complete recovery of brain function after stroke. Many animal models and clinical trials have demonstrated that neural stem cells (NSCs) in the central nervous system can orchestrate neurological repair through nerve regeneration, neuron polarization, axon pruning, neurite outgrowth, repair of myelin, and remodeling of the microenvironment and brain networks. Compared with other types of stem cells, NSCs have unique advantages in cell replacement, paracrine action, inflammatory regulation and neuroprotection. Our review summarizes NSC origins, characteristics, therapeutic mechanisms and repair processes, then highlights current research findings and clinical evidence for NSC therapy. These results may be helpful to inform the direction of future stroke research and to guide clinical decision-making.
Stroke is a main cause of death and disability worldwide. The ability of the brain to self-repair in the acute and chronic phases after stroke is minimal; however, promising stem cell-based interventions are emerging that may give substantial and possibly complete recovery of brain function after stroke. Many animal models and clinical trials have demonstrated that neural stem cells (NSCs) in the central nervous system can orchestrate neurological repair through nerve regeneration, neuron polarization, axon pruning, neurite outgrowth, repair of myelin, and remodeling of the microenvironment and brain networks. Compared with other types of stem cells, NSCs have unique advantages in cell replacement, paracrine action, inflammatory regulation and neuroprotection. Our review summarizes NSC origins, characteristics, therapeutic mechanisms and repair processes, then highlights current research findings and clinical evidence for NSC therapy. These results may be helpful to inform the direction of future stroke research and to guide clinical decision-making.Stroke is a main cause of death and disability worldwide. The ability of the brain to self-repair in the acute and chronic phases after stroke is minimal; however, promising stem cell-based interventions are emerging that may give substantial and possibly complete recovery of brain function after stroke. Many animal models and clinical trials have demonstrated that neural stem cells (NSCs) in the central nervous system can orchestrate neurological repair through nerve regeneration, neuron polarization, axon pruning, neurite outgrowth, repair of myelin, and remodeling of the microenvironment and brain networks. Compared with other types of stem cells, NSCs have unique advantages in cell replacement, paracrine action, inflammatory regulation and neuroprotection. Our review summarizes NSC origins, characteristics, therapeutic mechanisms and repair processes, then highlights current research findings and clinical evidence for NSC therapy. These results may be helpful to inform the direction of future stroke research and to guide clinical decision-making.
Audience Academic
Author Liu, Yu-Wan
Liu, Jing
Jiao, Yang
Chen, Wei-Gong
AuthorAffiliation Stem Cell Clinical Research Center,National Joint Engineering Laboratory,Regenerative Medicine Center,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province,China;Dalian Innovation Institute of Stem Cells and Precision Medicine,Dalian,Liaoning Province,China%Stem Cell Clinical Research Center,National Joint Engineering Laboratory,Regenerative Medicine Center,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province,China
AuthorAffiliation_xml – name: Stem Cell Clinical Research Center,National Joint Engineering Laboratory,Regenerative Medicine Center,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province,China;Dalian Innovation Institute of Stem Cells and Precision Medicine,Dalian,Liaoning Province,China%Stem Cell Clinical Research Center,National Joint Engineering Laboratory,Regenerative Medicine Center,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province,China
– name: 2 Dalian Innovation Institute of Stem Cells and Precision Medicine, Dalian, Liaoning Province, China
– name: 1 Stem Cell Clinical Research Center, National Joint Engineering Laboratory, Regenerative Medicine Center, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China
Author_xml – sequence: 1
  givenname: Yang
  surname: Jiao
  fullname: Jiao, Yang
  organization: Stem Cell Clinical Research Center, National Joint Engineering Laboratory, Regenerative Medicine Center, The First Affiliated Hospital of Dalian Medical University; Dalian Innovation Institute of Stem Cells and Precision Medicine, Dalian, Liaoning Province
– sequence: 2
  givenname: Yu-Wan
  surname: Liu
  fullname: Liu, Yu-Wan
  organization: Stem Cell Clinical Research Center, National Joint Engineering Laboratory, Regenerative Medicine Center, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province
– sequence: 3
  givenname: Wei-Gong
  surname: Chen
  fullname: Chen, Wei-Gong
  organization: Stem Cell Clinical Research Center, National Joint Engineering Laboratory, Regenerative Medicine Center, The First Affiliated Hospital of Dalian Medical University; Dalian Innovation Institute of Stem Cells and Precision Medicine, Dalian, Liaoning Province
– sequence: 4
  givenname: Jing
  surname: Liu
  fullname: Liu, Jing
  organization: Stem Cell Clinical Research Center, National Joint Engineering Laboratory, Regenerative Medicine Center, The First Affiliated Hospital of Dalian Medical University; Dalian Innovation Institute of Stem Cells and Precision Medicine, Dalian, Liaoning Province
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32788451$$D View this record in MEDLINE/PubMed
BookMark eNp9k9tr2zAUxs3oWC_b-56GYS-D4UwXy5L3MAhll0LZXrZnIcuSq9SRMslOSP_6HTdJ15QxbLAsfd9POsefz7MTH7zJstcYzUqM6AdccVowyssZEVXN2LPsDAteFbxm4gTGh-XT7DylBUJM1IS-yE4p4UKUDJ9l6-9mjCGazngT1eCCz5Vvczt6Pb2oPo9Gh7WJ21zZwcQ8DTHcmo-5atfKa-e73AMBdGkwy1ybvs-HG0CttvkQNiq2ue6ddxoUarXqYTBxX2bPreqTebV_XmS_vnz-efmtuP7x9epyfl1ojnlXYKFty6pKM2RZYxvdCC0ogSqahlvKG0SsanDdUMUELpVpypYJ0DBTE2M5vciudtw2qIVcRbdUcSuDcvJ-IsROqjg43RuJObWVJjWnDJWtIYIIo1pcVqxsmK0YsD7tWKuxWZpWGz9A3UfQ4xXvbmQX1pILLISoAPB-B9gob5Xv5CKMEVqc5F2XFndpu5CGIIIRXBTU7_bbxfB7NGmQS5em_ipvwpgkKWmJpo-LQPr2ifSBTBglNYK7-qvqFJTrvA1wSj1B5byCRHBB6bTt7B8quFqzdBriZx3MHxnePG7LQz8OGQNBtRPoGFKKxkrthvsUANn1EiM5hVlOaZVTQXIXZjCiJ8YD-z-W-b7FoYe0ptt-3Jgo4Vy3PmyOfMUjnxRIHn4E-gekKAuO
CitedBy_id crossref_primary_10_1097_HM9_0000000000000054
crossref_primary_10_3390_ijms23031601
crossref_primary_10_3390_biom11091316
crossref_primary_10_1016_j_brainresbull_2024_110999
crossref_primary_10_1002_nep3_27
crossref_primary_10_1016_j_biopha_2023_115507
crossref_primary_10_1016_j_heliyon_2024_e36748
crossref_primary_10_3233_JAD_220831
crossref_primary_10_1039_D2BM01790C
crossref_primary_10_3390_molecules29184439
crossref_primary_10_52586_5020
crossref_primary_10_1016_j_neuroscience_2024_05_027
crossref_primary_10_4103_NRR_NRR_D_23_01144
crossref_primary_10_1038_s43856_022_00105_8
crossref_primary_10_3390_cells13100790
crossref_primary_10_4252_wjsc_v13_i8_1030
crossref_primary_10_1186_s12883_022_02875_z
crossref_primary_10_1186_s41983_024_00851_7
crossref_primary_10_1248_bpb_b24_00501
crossref_primary_10_1097_JS9_0000000000002082
crossref_primary_10_1016_j_compositesb_2023_110711
crossref_primary_10_1016_j_bioadv_2023_213396
crossref_primary_10_1002_VIW_20200128
crossref_primary_10_4103_1673_5374_382256
crossref_primary_10_1016_j_expneurol_2023_114543
crossref_primary_10_3390_ijms22052258
crossref_primary_10_3390_pharmaceutics15041210
crossref_primary_10_1038_s41598_023_42743_5
crossref_primary_10_3390_bioengineering9110717
Cites_doi 10.3892/etm.2018.6848
10.2147/IJN.S175914
10.1161/STROKEAHA.106.475244
10.5966/sctm.2013-0117
10.1371/journal.pone.0049700
10.1007/s13311-018-0637-0
10.1212/WNL.0000000000000278
10.1016/j.cell.2012.08.020
10.1016/S0140-6736(16)30513-X
10.1038/s41586-018-0087-1
10.1016/j.lfs.2018.07.030
10.3727/096368912X656144
10.5966/sctm.2015-0414
10.1016/j.actbio.2017.07.013
10.3389/fnsys.2014.00116
10.1074/jbc.M112.410944
10.1177/1756286418789326
10.1016/S0140-6736(16)30962-X
10.1016/j.matbio.2016.09.007
10.1016/j.conb.2010.10.002
10.1161/STROKEAHA.109.575993
10.1007/s12975-016-0504-4
10.1089/scd.2016.0268
10.1038/s41582-018-0126-4
10.3348/kjr.2008.9.3.196
10.1146/annurev-cellbio-101011-155801
10.1371/journal.pone.0088810
10.1161/STROKEAHA.117.020353
10.1007/978-3-030-31206-0_4
10.1212/WNL.59.4.514
10.1016/j.transproceed.2010.05.029
10.1039/C9AN00347A
10.1002/smll.201202208
10.1002/brb3.972
10.1177/1545968309335978
10.1111/cns.12546
10.1002/hipo.22428
10.1016/j.neuroscience.2010.11.054
10.2147/JN.S148794
10.1038/s41467-017-00926-5
10.7150/thno.26643
10.26599/JNR.2018.9040002
10.1039/c2lc21285d
10.3389/fncel.2013.00182
10.1159/000086518
10.1634/stemcells.2008-0234
10.1161/STROKEAHA.116.012995
10.3109/1061186X.2013.878939
10.1186/s13287-018-0913-2
10.1007/s00018-015-2028-6
10.1212/WNL.0000000000002889
10.5966/sctm.2014-0184
10.1007/s00018-017-2586-x
10.1038/s41418-019-0314-9
10.1186/s13287-015-0124-z
10.1080/15384101.2018.1560201
10.1093/ons/opz204
10.1038/srep32291
10.1007/s12035-016-0350-0
10.1016/j.cell.2007.11.019
10.1002/dneu.22540
10.1007/s12975-016-0482-6
10.1016/j.celrep.2017.03.065
10.1016/j.molcel.2014.08.020
10.1006/exnr.1999.7337
10.1038/nn.3082
10.2174/15701611113119990016
10.1155/2018/4826407
10.1088/1748-605X/aa9a4b
10.1161/CIR.0000000000000485
10.1038/nn.3991
10.1016/j.cell.2006.07.024
10.3791/51433
10.12659/MSM.913777
10.1111/apha.12250
10.1016/0012-1606(84)90316-6
10.3390/jcm8040537
10.1038/bmt.2010.119
10.1038/nrn.2017.149
10.1517/14712598.4.2.131
10.1016/j.nbd.2017.01.010
10.1016/j.biomaterials.2015.08.041
10.1002/bit.26224
10.1016/j.tics.2017.09.012
10.1016/S0002-9440(10)62546-1
10.1002/glia.22406
10.1016/S0896-6273(01)00420-2
10.1016/j.pneurobio.2017.07.004
10.3727/096368912X657936
10.1161/CIRCRESAHA.116.308413
10.1007/s12035-016-0301-9
10.1016/j.scr.2017.07.015
10.1523/JNEUROSCI.5180-12.2013
10.1016/j.neulet.2018.10.002
10.1161/CIR.0000000000000659
10.1016/j.jbiosc.2017.05.014
10.1093/nar/gku594
10.1002/ana.22168
10.1016/j.stem.2018.05.014
10.1016/j.celrep.2017.07.051
10.1038/nn.3992
10.3727/096368912X633806
10.1080/15476278.2015.1011921
10.1016/j.ejcb.2009.02.001
10.1002/stem.779
10.1038/jcbfm.2012.187
10.1093/brain/awr094
10.1177/096368979900800106
10.1161/01.str.0000437068.30550.cf
10.3389/fncel.2017.00384
10.1523/JNEUROSCI.1339-15.2015
10.1007/s10529-009-9989-1
10.1172/JCI200420935
10.3171/jns.2005.103.1.0038
10.1016/j.neulet.2019.03.005
10.3171/2013.2.FOCUS12424
10.1016/j.actbio.2017.02.046
10.1016/j.expneurol.2015.10.013
10.1161/01.STR.0000196957.55928.ab
10.1523/JNEUROSCI.0525-17.2017
10.1016/j.neuroimage.2005.06.063
10.1016/j.neuint.2018.08.009
10.4103/1673-5374.264442
10.1155/2017/2934149
10.1073/pnas.242435499
10.1016/j.expneurol.2018.12.002
10.1016/j.neubiorev.2007.02.003
10.1371/journal.pbio.2006223
10.1111/j.1747-4949.2012.00797.x
10.1186/s13287-015-0015-3
10.1016/j.ijdevneu.2011.02.003
10.1016/j.pneurobio.2008.04.005
10.1111/ner.12484
10.1016/j.tig.2010.05.003
10.3171/2008.6.PEDS0834
10.3171/2016.2.FOCUS15637
10.1089/scd.2017.0009
10.1002/sctm.18-0220
10.1016/j.expneurol.2005.12.011
10.1016/j.celrep.2016.06.066
10.1016/j.conb.2016.05.004
10.1016/j.brainres.2015.02.042
10.2174/1871527313666141023094720
10.1002/brb3.1214
10.1007/s00401-017-1718-6
10.1016/j.bone.2015.04.044
10.1126/science.1238411
10.1038/nrneurol.2010.146
10.1063/1.4974902
10.1097/01.CCM.0000063047.63862.99
10.1038/nn.4193
10.1523/JNEUROSCI.2715-17.2018
10.1016/S0140-6736(13)60986-1
10.1002/ana.21517
10.1186/s12974-018-1379-y
10.1016/j.stem.2012.07.007
10.1093/brain/aww347
10.1016/j.neuroscience.2016.12.048
10.1007/s00221-016-4818-y
10.1371/journal.pone.0158044
10.1016/j.stem.2015.06.003
10.1016/j.stem.2015.06.007
10.1016/S0896-6273(02)00652-9
10.1126/science.1161151
10.1007/s12975-016-0460-z
10.4103/1673-5374.177739
10.1161/01.STR.0000083698.20199.1F
10.1038/s41593-018-0084-6
10.1007/s00018-014-1729-6
10.1042/BST20130194
10.3727/096368910X503406
10.1016/j.nano.2018.11.006
10.1016/j.actbio.2016.09.001
10.1016/j.stemcr.2015.02.022
10.1002/adma.201804041
10.4103/1673-5374.266062
10.1089/scd.2017.0225
10.1038/s41593-018-0168-3
10.1038/ncb3108
10.1016/S0140-6736(05)70233-6
10.1002/stem.1098
10.2174/1389450117666160613104523
10.1007/s11427-016-0114-9
10.1111/jcmm.13309
10.4103/1673-5374.251188
10.1038/nature22047
10.1016/j.jcms.2016.12.014
10.1073/pnas.1615322113
10.1016/j.stem.2016.03.020
10.1016/j.neurol.2017.09.003
10.1006/exnr.1997.6730
10.1089/scd.2013.0089
10.3389/fncel.2017.00176
10.1002/acn3.134
10.1002/stem.1104
10.3390/molecules21091143
10.1161/STROKEAHA.112.656900
10.1038/jcbfm.2014.41
ContentType Journal Article
Copyright COPYRIGHT 2021 Medknow Publications and Media Pvt. Ltd.
2021. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright © Wanfang Data Co. Ltd. All Rights Reserved.
Copyright: © 2021 Neural Regeneration Research 2021
Copyright_xml – notice: COPYRIGHT 2021 Medknow Publications and Media Pvt. Ltd.
– notice: 2021. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: Copyright © Wanfang Data Co. Ltd. All Rights Reserved.
– notice: Copyright: © 2021 Neural Regeneration Research 2021
DBID AAYXX
CITATION
NPM
K9.
7X8
2B.
4A8
92I
93N
PSX
TCJ
5PM
DOA
DOI 10.4103/1673-5374.286955
DatabaseName CrossRef
PubMed
ProQuest Health & Medical Complete (Alumni)
MEDLINE - Academic
Wanfang Data Journals - Hong Kong
WANFANG Data Centre
Wanfang Data Journals
万方数据期刊 - 香港版
China Online Journals (COJ)
China Online Journals (COJ)
PubMed Central (Full Participant titles)
DOAJ Open Access Full Text
DatabaseTitle CrossRef
PubMed
ProQuest Health & Medical Complete (Alumni)
MEDLINE - Academic
DatabaseTitleList


PubMed
ProQuest Health & Medical Complete (Alumni)

MEDLINE - Academic
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Anatomy & Physiology
EISSN 1876-7958
EndPage 92
ExternalDocumentID oai_doaj_org_article_173f6c2973504de2828ead14654b5f65
PMC7818886
zgsjzsyj_e202101013
A632778333
32788451
10_4103_1673_5374_286955
10.4103/1673-5374.286955_80_Neuroreg
Genre Journal Article
GeographicLocations China
GeographicLocations_xml – name: China
GrantInformation_xml – fundername: This work was supported by the National Natural Science Foundation of China, No. 81471308 ; (Program of China National Health Commission and National Medical Products Administration ); Liaoning Province Excellent Talent Program Project, No. XLYC1902031 ; Dalian Innovation Fund, No. 2018J11CY025
  funderid: (to JL); (Program of China National Health Commission and National Medical Products Administration ); (to JL); (to JL)
GroupedDBID ---
-SE
-S~
0R~
53G
5RS
5VR
5VS
7X7
8FI
92F
92I
ACGFS
ADBBV
ADJBI
AENEX
AFKRA
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AZQEC
BAWUL
BENPR
CAJEE
CCEZO
CHBEP
CIEJG
CS3
CW9
DIK
DU5
FA0
FDB
GROUPED_DOAJ
GX1
H13
IAO
IEA
IHR
ITC
KQ8
M2M
M48
M5~
NQ-
O9-
OK1
OVD
PGMZT
PIMPY
Q--
RMW
RPM
TCJ
TEORI
TGQ
U1G
U5O
W3E
WFFXF
--K
123
1B1
4.4
8FJ
AAEDT
AAKAS
AALRI
AAXUO
AAYXX
ABUWG
ABWVN
ACRPL
ADMUD
ADNMO
ADRAZ
ADZCM
AFUIB
CCPQU
CITATION
DWQXO
EBS
EJD
EMOBN
EO8
FYUFA
GNUQQ
HMCUK
HYE
HZ~
IHE
IPNFZ
M41
PHGZM
PHGZT
PSYQQ
RIG
ROL
RPZ
UKHRP
2B.
93N
AAXDM
ABXLX
NPM
K9.
7X8
4A8
PMFND
PSX
5PM
ID FETCH-LOGICAL-c717g-18cfd566c50f5bfbcb8c832892bb7f37b02fab19b3a5814aeb4d588c85e92ef73
IEDL.DBID M48
ISSN 1673-5374
IngestDate Wed Aug 27 01:25:27 EDT 2025
Thu Aug 21 18:21:06 EDT 2025
Thu May 29 04:06:14 EDT 2025
Sun Aug 24 03:52:30 EDT 2025
Fri Jul 25 20:43:16 EDT 2025
Tue Jun 17 21:00:01 EDT 2025
Tue Jun 10 20:51:16 EDT 2025
Thu Jan 02 22:57:57 EST 2025
Thu Apr 24 23:09:44 EDT 2025
Tue Jul 01 03:20:23 EDT 2025
Tue Jun 17 22:48:54 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Keywords stem cells
neurological function
regeneration
plasticity
cognitive impairment
recovery
brain
stroke
central nervous system
Language English
License http://creativecommons.org/licenses/by-nc-sa/4.0
This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c717g-18cfd566c50f5bfbcb8c832892bb7f37b02fab19b3a5814aeb4d588c85e92ef73
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
Author contributions: All authors designed this manuscript and defined intellectual contents, contributed to manuscript writing, and approved the final version of this manuscript.
ORCID 0000-0001-8476-7978
0000-0002-0493-296X
OpenAccessLink http://journals.scholarsportal.info/openUrl.xqy?doi=10.4103/1673-5374.286955
PMID 32788451
PQID 2532902906
PQPubID 4671210
PageCount 13
ParticipantIDs doaj_primary_oai_doaj_org_article_173f6c2973504de2828ead14654b5f65
pubmedcentral_primary_oai_pubmedcentral_nih_gov_7818886
wanfang_journals_zgsjzsyj_e202101013
proquest_miscellaneous_2434053740
proquest_journals_2532902906
gale_infotracmisc_A632778333
gale_infotracacademiconefile_A632778333
pubmed_primary_32788451
crossref_citationtrail_10_4103_1673_5374_286955
crossref_primary_10_4103_1673_5374_286955
wolterskluwer_medknow_10_4103_1673-5374_286955_80_Neuroreg
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 20210101
PublicationDateYYYYMMDD 2021-01-01
PublicationDate_xml – month: 1
  year: 2021
  text: 20210101
  day: 01
PublicationDecade 2020
PublicationPlace India
PublicationPlace_xml – name: India
– name: Mumbai
PublicationTitle Neural regeneration research
PublicationTitleAlternate Neural Regen Res
PublicationTitle_FL Neural Regeneration Research
PublicationYear 2021
Publisher Wolters Kluwer India Pvt. Ltd
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Stem Cell Clinical Research Center,National Joint Engineering Laboratory,Regenerative Medicine Center,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province,China
Dalian Innovation Institute of Stem Cells and Precision Medicine,Dalian,Liaoning Province,China%Stem Cell Clinical Research Center,National Joint Engineering Laboratory,Regenerative Medicine Center,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province,China
Wolters Kluwer - Medknow
Wolters Kluwer Medknow Publications
Publisher_xml – name: Wolters Kluwer India Pvt. Ltd
– name: Medknow Publications and Media Pvt. Ltd
– name: Medknow Publications & Media Pvt. Ltd
– name: Stem Cell Clinical Research Center,National Joint Engineering Laboratory,Regenerative Medicine Center,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province,China
– name: Dalian Innovation Institute of Stem Cells and Precision Medicine,Dalian,Liaoning Province,China%Stem Cell Clinical Research Center,National Joint Engineering Laboratory,Regenerative Medicine Center,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province,China
– name: Wolters Kluwer - Medknow
– name: Wolters Kluwer Medknow Publications
References key-10.4103/1673-5374.286955-131
key-10.4103/1673-5374.286955-132
key-10.4103/1673-5374.286955-133
key-10.4103/1673-5374.286955-134
key-10.4103/1673-5374.286955-135
key-10.4103/1673-5374.286955-136
key-10.4103/1673-5374.286955-137
key-10.4103/1673-5374.286955-138
key-10.4103/1673-5374.286955-139
key-10.4103/1673-5374.286955-140
key-10.4103/1673-5374.286955-141
key-10.4103/1673-5374.286955-142
key-10.4103/1673-5374.286955-143
key-10.4103/1673-5374.286955-144
key-10.4103/1673-5374.286955-145
key-10.4103/1673-5374.286955-146
key-10.4103/1673-5374.286955-147
key-10.4103/1673-5374.286955-148
key-10.4103/1673-5374.286955-149
key-10.4103/1673-5374.286955-150
key-10.4103/1673-5374.286955-151
key-10.4103/1673-5374.286955-110
key-10.4103/1673-5374.286955-111
key-10.4103/1673-5374.286955-112
key-10.4103/1673-5374.286955-113
key-10.4103/1673-5374.286955-114
key-10.4103/1673-5374.286955-115
key-10.4103/1673-5374.286955-116
key-10.4103/1673-5374.286955-117
key-10.4103/1673-5374.286955-118
key-10.4103/1673-5374.286955-119
key-10.4103/1673-5374.286955-120
key-10.4103/1673-5374.286955-122
key-10.4103/1673-5374.286955-123
key-10.4103/1673-5374.286955-124
key-10.4103/1673-5374.286955-125
key-10.4103/1673-5374.286955-126
key-10.4103/1673-5374.286955-127
key-10.4103/1673-5374.286955-128
key-10.4103/1673-5374.286955-129
Schmidt-Hieber (key-10.4103/1673-5374.286955-152) 2004
key-10.4103/1673-5374.286955-130
key-10.4103/1673-5374.286955-175
key-10.4103/1673-5374.286955-176
key-10.4103/1673-5374.286955-177
key-10.4103/1673-5374.286955-178
key-10.4103/1673-5374.286955-179
key-10.4103/1673-5374.286955-180
key-10.4103/1673-5374.286955-181
key-10.4103/1673-5374.286955-182
key-10.4103/1673-5374.286955-183
key-10.4103/1673-5374.286955-184
key-10.4103/1673-5374.286955-185
key-10.4103/1673-5374.286955-186
key-10.4103/1673-5374.286955-187
key-10.4103/1673-5374.286955-188
key-10.4103/1673-5374.286955-189
key-10.4103/1673-5374.286955-190
key-10.4103/1673-5374.286955-191
key-10.4103/1673-5374.286955-192
key-10.4103/1673-5374.286955-193
key-10.4103/1673-5374.286955-194
key-10.4103/1673-5374.286955-195
key-10.4103/1673-5374.286955-196
key-10.4103/1673-5374.286955-153
key-10.4103/1673-5374.286955-154
key-10.4103/1673-5374.286955-155
key-10.4103/1673-5374.286955-156
key-10.4103/1673-5374.286955-157
key-10.4103/1673-5374.286955-158
key-10.4103/1673-5374.286955-90
key-10.4103/1673-5374.286955-159
key-10.4103/1673-5374.286955-91
key-10.4103/1673-5374.286955-92
key-10.4103/1673-5374.286955-93
key-10.4103/1673-5374.286955-94
key-10.4103/1673-5374.286955-95
key-10.4103/1673-5374.286955-96
key-10.4103/1673-5374.286955-97
key-10.4103/1673-5374.286955-98
key-10.4103/1673-5374.286955-99
key-10.4103/1673-5374.286955-160
key-10.4103/1673-5374.286955-161
key-10.4103/1673-5374.286955-162
key-10.4103/1673-5374.286955-163
key-10.4103/1673-5374.286955-164
key-10.4103/1673-5374.286955-165
key-10.4103/1673-5374.286955-166
key-10.4103/1673-5374.286955-167
key-10.4103/1673-5374.286955-168
key-10.4103/1673-5374.286955-169
key-10.4103/1673-5374.286955-170
key-10.4103/1673-5374.286955-171
key-10.4103/1673-5374.286955-172
key-10.4103/1673-5374.286955-173
key-10.4103/1673-5374.286955-174
Anderson (key-10.4103/1673-5374.286955-7) 2017
key-10.4103/1673-5374.286955-70
key-10.4103/1673-5374.286955-71
key-10.4103/1673-5374.286955-72
key-10.4103/1673-5374.286955-73
key-10.4103/1673-5374.286955-74
key-10.4103/1673-5374.286955-75
key-10.4103/1673-5374.286955-76
key-10.4103/1673-5374.286955-77
key-10.4103/1673-5374.286955-78
key-10.4103/1673-5374.286955-79
Mondello (key-10.4103/1673-5374.286955-121) 2014
key-10.4103/1673-5374.286955-80
key-10.4103/1673-5374.286955-81
key-10.4103/1673-5374.286955-82
key-10.4103/1673-5374.286955-83
key-10.4103/1673-5374.286955-85
key-10.4103/1673-5374.286955-86
key-10.4103/1673-5374.286955-87
key-10.4103/1673-5374.286955-88
key-10.4103/1673-5374.286955-89
key-10.4103/1673-5374.286955-197
key-10.4103/1673-5374.286955-198
key-10.4103/1673-5374.286955-199
key-10.4103/1673-5374.286955-50
key-10.4103/1673-5374.286955-51
key-10.4103/1673-5374.286955-52
key-10.4103/1673-5374.286955-53
key-10.4103/1673-5374.286955-54
key-10.4103/1673-5374.286955-55
key-10.4103/1673-5374.286955-56
key-10.4103/1673-5374.286955-57
key-10.4103/1673-5374.286955-58
key-10.4103/1673-5374.286955-59
key-10.4103/1673-5374.286955-60
key-10.4103/1673-5374.286955-61
key-10.4103/1673-5374.286955-62
key-10.4103/1673-5374.286955-63
key-10.4103/1673-5374.286955-64
key-10.4103/1673-5374.286955-65
key-10.4103/1673-5374.286955-66
key-10.4103/1673-5374.286955-67
key-10.4103/1673-5374.286955-68
key-10.4103/1673-5374.286955-69
key-10.4103/1673-5374.286955-8
key-10.4103/1673-5374.286955-9
key-10.4103/1673-5374.286955-4
key-10.4103/1673-5374.286955-3
key-10.4103/1673-5374.286955-6
key-10.4103/1673-5374.286955-5
key-10.4103/1673-5374.286955-30
key-10.4103/1673-5374.286955-31
key-10.4103/1673-5374.286955-2
key-10.4103/1673-5374.286955-32
key-10.4103/1673-5374.286955-1
key-10.4103/1673-5374.286955-33
key-10.4103/1673-5374.286955-34
Ievins (key-10.4103/1673-5374.286955-84) 2017
key-10.4103/1673-5374.286955-35
key-10.4103/1673-5374.286955-36
key-10.4103/1673-5374.286955-37
key-10.4103/1673-5374.286955-38
key-10.4103/1673-5374.286955-39
key-10.4103/1673-5374.286955-100
key-10.4103/1673-5374.286955-101
key-10.4103/1673-5374.286955-102
key-10.4103/1673-5374.286955-103
key-10.4103/1673-5374.286955-104
key-10.4103/1673-5374.286955-105
key-10.4103/1673-5374.286955-106
key-10.4103/1673-5374.286955-107
key-10.4103/1673-5374.286955-108
key-10.4103/1673-5374.286955-40
key-10.4103/1673-5374.286955-109
key-10.4103/1673-5374.286955-41
key-10.4103/1673-5374.286955-42
key-10.4103/1673-5374.286955-43
key-10.4103/1673-5374.286955-44
key-10.4103/1673-5374.286955-45
key-10.4103/1673-5374.286955-46
key-10.4103/1673-5374.286955-47
key-10.4103/1673-5374.286955-48
key-10.4103/1673-5374.286955-49
key-10.4103/1673-5374.286955-10
key-10.4103/1673-5374.286955-11
key-10.4103/1673-5374.286955-12
key-10.4103/1673-5374.286955-13
key-10.4103/1673-5374.286955-14
key-10.4103/1673-5374.286955-15
key-10.4103/1673-5374.286955-16
key-10.4103/1673-5374.286955-17
key-10.4103/1673-5374.286955-18
key-10.4103/1673-5374.286955-19
key-10.4103/1673-5374.286955-200
key-10.4103/1673-5374.286955-201
key-10.4103/1673-5374.286955-202
key-10.4103/1673-5374.286955-203
key-10.4103/1673-5374.286955-204
key-10.4103/1673-5374.286955-205
key-10.4103/1673-5374.286955-206
key-10.4103/1673-5374.286955-207
key-10.4103/1673-5374.286955-20
key-10.4103/1673-5374.286955-21
key-10.4103/1673-5374.286955-22
key-10.4103/1673-5374.286955-23
key-10.4103/1673-5374.286955-24
key-10.4103/1673-5374.286955-25
key-10.4103/1673-5374.286955-26
key-10.4103/1673-5374.286955-27
key-10.4103/1673-5374.286955-28
key-10.4103/1673-5374.286955-29
References_xml – ident: key-10.4103/1673-5374.286955-173
  doi: 10.3892/etm.2018.6848
– ident: key-10.4103/1673-5374.286955-206
  doi: 10.2147/IJN.S175914
– start-page: 2950
  volume-title: Safety of autologous human schwann cell transplantation in subacute thoracic spinal cord injury
  year: 2017
  ident: key-10.4103/1673-5374.286955-7
  publication-title: J Neurotrauma
– ident: key-10.4103/1673-5374.286955-95
  doi: 10.1161/STROKEAHA.106.475244
– ident: key-10.4103/1673-5374.286955-107
  doi: 10.5966/sctm.2013-0117
– ident: key-10.4103/1673-5374.286955-41
  doi: 10.1371/journal.pone.0049700
– ident: key-10.4103/1673-5374.286955-123
  doi: 10.1007/s13311-018-0637-0
– start-page: 184
  volume-title: Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus
  year: 2004
  ident: key-10.4103/1673-5374.286955-152
  publication-title: Nature
– ident: key-10.4103/1673-5374.286955-183
  doi: 10.1212/WNL.0000000000000278
– ident: key-10.4103/1673-5374.286955-108
  doi: 10.1016/j.cell.2012.08.020
– ident: key-10.4103/1673-5374.286955-88
  doi: 10.1016/S0140-6736(16)30513-X
– ident: key-10.4103/1673-5374.286955-19
  doi: 10.1038/s41586-018-0087-1
– ident: key-10.4103/1673-5374.286955-65
  doi: 10.1016/j.lfs.2018.07.030
– ident: key-10.4103/1673-5374.286955-42
  doi: 10.3727/096368912X656144
– ident: key-10.4103/1673-5374.286955-117
  doi: 10.5966/sctm.2015-0414
– ident: key-10.4103/1673-5374.286955-157
  doi: 10.1016/j.actbio.2017.07.013
– ident: key-10.4103/1673-5374.286955-169
  doi: 10.3389/fnsys.2014.00116
– ident: key-10.4103/1673-5374.286955-122
  doi: 10.1074/jbc.M112.410944
– ident: key-10.4103/1673-5374.286955-48
  doi: 10.1177/1756286418789326
– ident: key-10.4103/1673-5374.286955-73
  doi: 10.1016/S0140-6736(16)30962-X
– ident: key-10.4103/1673-5374.286955-1
  doi: 10.1016/j.matbio.2016.09.007
– ident: key-10.4103/1673-5374.286955-60
– ident: key-10.4103/1673-5374.286955-57
  doi: 10.1016/j.conb.2010.10.002
– ident: key-10.4103/1673-5374.286955-138
  doi: 10.1161/STROKEAHA.109.575993
– ident: key-10.4103/1673-5374.286955-32
  doi: 10.1007/s12975-016-0504-4
– ident: key-10.4103/1673-5374.286955-149
  doi: 10.1089/scd.2016.0268
– ident: key-10.4103/1673-5374.286955-201
  doi: 10.1038/s41582-018-0126-4
– ident: key-10.4103/1673-5374.286955-33
  doi: 10.3348/kjr.2008.9.3.196
– ident: key-10.4103/1673-5374.286955-175
  doi: 10.1146/annurev-cellbio-101011-155801
– ident: key-10.4103/1673-5374.286955-53
  doi: 10.1371/journal.pone.0088810
– ident: key-10.4103/1673-5374.286955-185
  doi: 10.1161/STROKEAHA.117.020353
– ident: key-10.4103/1673-5374.286955-181
  doi: 10.1007/978-3-030-31206-0_4
– ident: key-10.4103/1673-5374.286955-102
  doi: 10.1212/WNL.59.4.514
– ident: key-10.4103/1673-5374.286955-29
  doi: 10.1016/j.transproceed.2010.05.029
– ident: key-10.4103/1673-5374.286955-103
  doi: 10.1039/C9AN00347A
– ident: key-10.4103/1673-5374.286955-188
  doi: 10.1002/smll.201202208
– ident: key-10.4103/1673-5374.286955-97
  doi: 10.1002/brb3.972
– ident: key-10.4103/1673-5374.286955-165
  doi: 10.1177/1545968309335978
– ident: key-10.4103/1673-5374.286955-168
  doi: 10.1111/cns.12546
– ident: key-10.4103/1673-5374.286955-21
  doi: 10.1002/hipo.22428
– ident: key-10.4103/1673-5374.286955-71
  doi: 10.1016/j.neuroscience.2010.11.054
– ident: key-10.4103/1673-5374.286955-114
  doi: 10.2147/JN.S148794
– ident: key-10.4103/1673-5374.286955-124
  doi: 10.1038/s41467-017-00926-5
– ident: key-10.4103/1673-5374.286955-192
  doi: 10.7150/thno.26643
– ident: key-10.4103/1673-5374.286955-113
  doi: 10.26599/JNR.2018.9040002
– ident: key-10.4103/1673-5374.286955-72
  doi: 10.1039/c2lc21285d
– ident: key-10.4103/1673-5374.286955-58
  doi: 10.3389/fncel.2013.00182
– ident: key-10.4103/1673-5374.286955-151
  doi: 10.1159/000086518
– ident: key-10.4103/1673-5374.286955-125
  doi: 10.1634/stemcells.2008-0234
– ident: key-10.4103/1673-5374.286955-161
  doi: 10.1161/STROKEAHA.116.012995
– ident: key-10.4103/1673-5374.286955-68
  doi: 10.3109/1061186X.2013.878939
– ident: key-10.4103/1673-5374.286955-27
  doi: 10.1186/s13287-018-0913-2
– ident: key-10.4103/1673-5374.286955-22
  doi: 10.1007/s00018-015-2028-6
– ident: key-10.4103/1673-5374.286955-62
  doi: 10.1212/WNL.0000000000002889
– ident: key-10.4103/1673-5374.286955-51
  doi: 10.5966/sctm.2014-0184
– ident: key-10.4103/1673-5374.286955-141
  doi: 10.1007/s00018-017-2586-x
– ident: key-10.4103/1673-5374.286955-106
  doi: 10.1038/s41418-019-0314-9
– ident: key-10.4103/1673-5374.286955-176
  doi: 10.1186/s13287-015-0124-z
– ident: key-10.4103/1673-5374.286955-191
  doi: 10.1080/15384101.2018.1560201
– ident: key-10.4103/1673-5374.286955-197
  doi: 10.1093/ons/opz204
– ident: key-10.4103/1673-5374.286955-34
  doi: 10.1038/srep32291
– ident: key-10.4103/1673-5374.286955-6
  doi: 10.1007/s12035-016-0350-0
– ident: key-10.4103/1673-5374.286955-171
  doi: 10.1016/j.cell.2007.11.019
– ident: key-10.4103/1673-5374.286955-93
  doi: 10.1002/dneu.22540
– ident: key-10.4103/1673-5374.286955-174
– ident: key-10.4103/1673-5374.286955-144
  doi: 10.1007/s12975-016-0482-6
– ident: key-10.4103/1673-5374.286955-10
  doi: 10.1016/j.celrep.2017.03.065
– ident: key-10.4103/1673-5374.286955-37
  doi: 10.1016/j.molcel.2014.08.020
– ident: key-10.4103/1673-5374.286955-18
  doi: 10.1006/exnr.1999.7337
– ident: key-10.4103/1673-5374.286955-43
  doi: 10.1038/nn.3082
– ident: key-10.4103/1673-5374.286955-190
  doi: 10.2174/15701611113119990016
– ident: key-10.4103/1673-5374.286955-82
  doi: 10.1155/2018/4826407
– ident: key-10.4103/1673-5374.286955-166
  doi: 10.1088/1748-605X/aa9a4b
– ident: key-10.4103/1673-5374.286955-23
  doi: 10.1161/CIR.0000000000000485
– ident: key-10.4103/1673-5374.286955-118
  doi: 10.1038/nn.3991
– ident: key-10.4103/1673-5374.286955-170
  doi: 10.1016/j.cell.2006.07.024
– ident: key-10.4103/1673-5374.286955-89
  doi: 10.3791/51433
– ident: key-10.4103/1673-5374.286955-50
  doi: 10.12659/MSM.913777
– ident: key-10.4103/1673-5374.286955-126
  doi: 10.1111/apha.12250
– ident: key-10.4103/1673-5374.286955-9
  doi: 10.1016/0012-1606(84)90316-6
– ident: key-10.4103/1673-5374.286955-193
  doi: 10.3390/jcm8040537
– ident: key-10.4103/1673-5374.286955-159
  doi: 10.1038/bmt.2010.119
– ident: key-10.4103/1673-5374.286955-14
  doi: 10.1038/nrn.2017.149
– ident: key-10.4103/1673-5374.286955-78
  doi: 10.1517/14712598.4.2.131
– ident: key-10.4103/1673-5374.286955-135
  doi: 10.1016/j.nbd.2017.01.010
– ident: key-10.4103/1673-5374.286955-2
  doi: 10.1016/j.biomaterials.2015.08.041
– ident: key-10.4103/1673-5374.286955-61
  doi: 10.1002/bit.26224
– ident: key-10.4103/1673-5374.286955-129
  doi: 10.1016/j.tics.2017.09.012
– ident: key-10.4103/1673-5374.286955-130
  doi: 10.1016/S0002-9440(10)62546-1
– ident: key-10.4103/1673-5374.286955-30
  doi: 10.1002/glia.22406
– ident: key-10.4103/1673-5374.286955-119
  doi: 10.1016/S0896-6273(01)00420-2
– ident: key-10.4103/1673-5374.286955-164
  doi: 10.1016/j.pneurobio.2017.07.004
– ident: key-10.4103/1673-5374.286955-79
  doi: 10.3727/096368912X657936
– ident: key-10.4103/1673-5374.286955-52
  doi: 10.1161/CIRCRESAHA.116.308413
– ident: key-10.4103/1673-5374.286955-45
  doi: 10.1007/s12035-016-0301-9
– ident: key-10.4103/1673-5374.286955-59
  doi: 10.1016/j.scr.2017.07.015
– ident: key-10.4103/1673-5374.286955-200
  doi: 10.1523/JNEUROSCI.5180-12.2013
– ident: key-10.4103/1673-5374.286955-202
  doi: 10.1016/j.neulet.2018.10.002
– ident: key-10.4103/1673-5374.286955-24
  doi: 10.1161/CIR.0000000000000659
– ident: key-10.4103/1673-5374.286955-25
  doi: 10.1016/j.jbiosc.2017.05.014
– ident: key-10.4103/1673-5374.286955-66
  doi: 10.1093/nar/gku594
– ident: key-10.4103/1673-5374.286955-133
  doi: 10.1002/ana.22168
– ident: key-10.4103/1673-5374.286955-39
  doi: 10.1016/j.stem.2018.05.014
– ident: key-10.4103/1673-5374.286955-112
  doi: 10.1016/j.celrep.2017.07.051
– ident: key-10.4103/1673-5374.286955-80
  doi: 10.1038/nn.3992
– ident: key-10.4103/1673-5374.286955-110
  doi: 10.3727/096368912X633806
– ident: key-10.4103/1673-5374.286955-40
  doi: 10.1080/15476278.2015.1011921
– ident: key-10.4103/1673-5374.286955-44
  doi: 10.1016/j.ejcb.2009.02.001
– ident: key-10.4103/1673-5374.286955-54
  doi: 10.1002/stem.779
– ident: key-10.4103/1673-5374.286955-55
  doi: 10.1038/jcbfm.2012.187
– ident: key-10.4103/1673-5374.286955-8
  doi: 10.1093/brain/awr094
– ident: key-10.4103/1673-5374.286955-83
  doi: 10.1177/096368979900800106
– ident: key-10.4103/1673-5374.286955-96
  doi: 10.1161/01.str.0000437068.30550.cf
– ident: key-10.4103/1673-5374.286955-11
  doi: 10.3389/fncel.2017.00384
– ident: key-10.4103/1673-5374.286955-67
  doi: 10.1523/JNEUROSCI.1339-15.2015
– ident: key-10.4103/1673-5374.286955-177
  doi: 10.1007/s10529-009-9989-1
– ident: key-10.4103/1673-5374.286955-47
  doi: 10.1172/JCI200420935
– ident: key-10.4103/1673-5374.286955-94
  doi: 10.3171/jns.2005.103.1.0038
– ident: key-10.4103/1673-5374.286955-86
  doi: 10.1016/j.neulet.2019.03.005
– ident: key-10.4103/1673-5374.286955-172
  doi: 10.3171/2013.2.FOCUS12424
– ident: key-10.4103/1673-5374.286955-127
  doi: 10.1016/j.actbio.2017.02.046
– ident: key-10.4103/1673-5374.286955-132
  doi: 10.1016/j.expneurol.2015.10.013
– ident: key-10.4103/1673-5374.286955-150
  doi: 10.1161/01.STR.0000196957.55928.ab
– ident: key-10.4103/1673-5374.286955-38
  doi: 10.1523/JNEUROSCI.0525-17.2017
– ident: key-10.4103/1673-5374.286955-87
  doi: 10.1016/j.neuroimage.2005.06.063
– ident: key-10.4103/1673-5374.286955-64
  doi: 10.1016/j.neuint.2018.08.009
– ident: key-10.4103/1673-5374.286955-76
  doi: 10.4103/1673-5374.264442
– ident: key-10.4103/1673-5374.286955-205
  doi: 10.1155/2017/2934149
– ident: key-10.4103/1673-5374.286955-81
  doi: 10.1073/pnas.242435499
– ident: key-10.4103/1673-5374.286955-139
  doi: 10.1016/j.expneurol.2018.12.002
– ident: key-10.4103/1673-5374.286955-105
  doi: 10.1016/j.neubiorev.2007.02.003
– ident: key-10.4103/1673-5374.286955-100
  doi: 10.1371/journal.pbio.2006223
– ident: key-10.4103/1673-5374.286955-99
  doi: 10.1111/j.1747-4949.2012.00797.x
– ident: key-10.4103/1673-5374.286955-131
  doi: 10.1186/s13287-015-0015-3
– ident: key-10.4103/1673-5374.286955-203
  doi: 10.1016/j.ijdevneu.2011.02.003
– ident: key-10.4103/1673-5374.286955-75
  doi: 10.1016/j.pneurobio.2008.04.005
– ident: key-10.4103/1673-5374.286955-63
  doi: 10.1111/ner.12484
– ident: key-10.4103/1673-5374.286955-111
  doi: 10.1016/j.tig.2010.05.003
– ident: key-10.4103/1673-5374.286955-128
  doi: 10.3171/2008.6.PEDS0834
– ident: key-10.4103/1673-5374.286955-15
  doi: 10.3171/2016.2.FOCUS15637
– ident: key-10.4103/1673-5374.286955-158
  doi: 10.1089/scd.2017.0009
– ident: key-10.4103/1673-5374.286955-198
  doi: 10.1002/sctm.18-0220
– ident: key-10.4103/1673-5374.286955-140
  doi: 10.1016/j.expneurol.2005.12.011
– ident: key-10.4103/1673-5374.286955-186
  doi: 10.1016/j.celrep.2016.06.066
– ident: key-10.4103/1673-5374.286955-187
  doi: 10.1016/j.conb.2016.05.004
– ident: key-10.4103/1673-5374.286955-146
  doi: 10.1016/j.brainres.2015.02.042
– ident: key-10.4103/1673-5374.286955-4
  doi: 10.2174/1871527313666141023094720
– ident: key-10.4103/1673-5374.286955-17
  doi: 10.1002/brb3.1214
– ident: key-10.4103/1673-5374.286955-120
– ident: key-10.4103/1673-5374.286955-16
  doi: 10.1007/s00401-017-1718-6
– ident: key-10.4103/1673-5374.286955-109
– ident: key-10.4103/1673-5374.286955-98
  doi: 10.1016/j.bone.2015.04.044
– ident: key-10.4103/1673-5374.286955-137
  doi: 10.1126/science.1238411
– ident: key-10.4103/1673-5374.286955-3
  doi: 10.1038/nrneurol.2010.146
– ident: key-10.4103/1673-5374.286955-184
  doi: 10.1063/1.4974902
– ident: key-10.4103/1673-5374.286955-143
  doi: 10.1097/01.CCM.0000063047.63862.99
– ident: key-10.4103/1673-5374.286955-179
  doi: 10.1038/nn.4193
– ident: key-10.4103/1673-5374.286955-69
  doi: 10.1523/JNEUROSCI.2715-17.2018
– ident: key-10.4103/1673-5374.286955-115
  doi: 10.1016/S0140-6736(13)60986-1
– start-page: 21
  volume-title: Therapeutic intraspinal stimulation to generate activity and promote long-term recovery
  year: 2014
  ident: key-10.4103/1673-5374.286955-121
  publication-title: Front Neurosci
– ident: key-10.4103/1673-5374.286955-163
  doi: 10.1002/ana.21517
– ident: key-10.4103/1673-5374.286955-189
  doi: 10.1186/s12974-018-1379-y
– ident: key-10.4103/1673-5374.286955-90
  doi: 10.1016/j.stem.2012.07.007
– ident: key-10.4103/1673-5374.286955-178
  doi: 10.1093/brain/aww347
– ident: key-10.4103/1673-5374.286955-36
  doi: 10.1016/j.neuroscience.2016.12.048
– ident: key-10.4103/1673-5374.286955-156
  doi: 10.1007/s00221-016-4818-y
– ident: key-10.4103/1673-5374.286955-204
  doi: 10.1371/journal.pone.0158044
– start-page: 391
  volume-title: Therapeutic stimulation for restoration of function after spinal cord injury
  year: 2017
  ident: key-10.4103/1673-5374.286955-84
  publication-title: Physiology (Bethesda)
– ident: key-10.4103/1673-5374.286955-101
  doi: 10.1016/j.stem.2015.06.003
– ident: key-10.4103/1673-5374.286955-154
– ident: key-10.4103/1673-5374.286955-180
  doi: 10.1016/j.stem.2015.06.007
– ident: key-10.4103/1673-5374.286955-162
  doi: 10.1016/S0896-6273(02)00652-9
– ident: key-10.4103/1673-5374.286955-13
  doi: 10.1126/science.1161151
– ident: key-10.4103/1673-5374.286955-92
  doi: 10.1007/s12975-016-0460-z
– ident: key-10.4103/1673-5374.286955-147
  doi: 10.4103/1673-5374.177739
– ident: key-10.4103/1673-5374.286955-85
  doi: 10.1161/01.STR.0000083698.20199.1F
– ident: key-10.4103/1673-5374.286955-26
  doi: 10.1038/s41593-018-0084-6
– ident: key-10.4103/1673-5374.286955-153
  doi: 10.1007/s00018-014-1729-6
– ident: key-10.4103/1673-5374.286955-20
  doi: 10.1042/BST20130194
– ident: key-10.4103/1673-5374.286955-182
  doi: 10.3727/096368910X503406
– ident: key-10.4103/1673-5374.286955-5
  doi: 10.1016/j.nano.2018.11.006
– ident: key-10.4103/1673-5374.286955-155
  doi: 10.1016/j.actbio.2016.09.001
– ident: key-10.4103/1673-5374.286955-70
  doi: 10.1016/j.stemcr.2015.02.022
– ident: key-10.4103/1673-5374.286955-12
  doi: 10.1002/adma.201804041
– ident: key-10.4103/1673-5374.286955-35
  doi: 10.4103/1673-5374.266062
– ident: key-10.4103/1673-5374.286955-196
  doi: 10.1089/scd.2017.0225
– ident: key-10.4103/1673-5374.286955-91
  doi: 10.1038/s41593-018-0168-3
– ident: key-10.4103/1673-5374.286955-77
  doi: 10.1038/ncb3108
– ident: key-10.4103/1673-5374.286955-116
  doi: 10.1016/S0140-6736(05)70233-6
– ident: key-10.4103/1673-5374.286955-49
  doi: 10.1002/stem.1098
– ident: key-10.4103/1673-5374.286955-136
  doi: 10.2174/1389450117666160613104523
– ident: key-10.4103/1673-5374.286955-194
  doi: 10.1007/s11427-016-0114-9
– ident: key-10.4103/1673-5374.286955-207
  doi: 10.1111/jcmm.13309
– ident: key-10.4103/1673-5374.286955-104
  doi: 10.4103/1673-5374.251188
– ident: key-10.4103/1673-5374.286955-142
  doi: 10.1038/nature22047
– ident: key-10.4103/1673-5374.286955-31
  doi: 10.1016/j.jcms.2016.12.014
– ident: key-10.4103/1673-5374.286955-160
  doi: 10.1073/pnas.1615322113
– ident: key-10.4103/1673-5374.286955-199
  doi: 10.1016/j.stem.2016.03.020
– ident: key-10.4103/1673-5374.286955-46
  doi: 10.1016/j.neurol.2017.09.003
– ident: key-10.4103/1673-5374.286955-28
  doi: 10.1006/exnr.1997.6730
– ident: key-10.4103/1673-5374.286955-145
  doi: 10.1089/scd.2013.0089
– ident: key-10.4103/1673-5374.286955-74
  doi: 10.3389/fncel.2017.00176
– ident: key-10.4103/1673-5374.286955-167
  doi: 10.1002/acn3.134
– ident: key-10.4103/1673-5374.286955-134
  doi: 10.1002/stem.1104
– ident: key-10.4103/1673-5374.286955-195
  doi: 10.3390/molecules21091143
– ident: key-10.4103/1673-5374.286955-148
  doi: 10.1161/STROKEAHA.112.656900
– ident: key-10.4103/1673-5374.286955-56
  doi: 10.1038/jcbfm.2014.41
SSID ssj0058923
Score 2.393957
SecondaryResourceType review_article
Snippet Stroke is a main cause of death and disability worldwide. The ability of the brain to self-repair in the acute and chronic phases after stroke is minimal;...
SourceID doaj
pubmedcentral
wanfang
proquest
gale
pubmed
crossref
wolterskluwer
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 80
SubjectTerms Brain research
brain; central nervous system; cognitive impairment; neurological function; plasticity; recovery; regeneration; stem cells; stroke
Care and treatment
Nervous system
Neurological research
Patient outcomes
Regeneration
Review
Stem cells
Stroke
Stroke (Disease)
Transplantation
SummonAdditionalLinks – databaseName: DOAJ Open Access Full Text
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELZQJSQuCCiPQEFGqkAcwiaxHTu9LYiqQoITlXqzbMdZ6COLNttW21_fGTtZEpDggnKLJ4ntmcx47JlvCNnPyqKwTtoUTKtNeakc6EGWpZ5VDazHnVcW852_fC2PjvnnE3EyKvWFMWERHjhO3CyXrCkdVlgSGa89eggw-BxhwKxoyoBeCjZvcKaiDhaqCoXd8lKyVDDJ4wElzzM22957X6iywhS_kUEKuP1_aueRefo9dPLutWkb0y6g5XqJB9zdWYhvH1mpwwfkfr-8pPM4rIfkjm8fkd15C671xYa-oSHgM-yk75KrAMyx8ouAPI0MoqatKVq6uEFI0VsGUd_QUEmcduvV8swf0Bg3ADaPIhom0CEYNMUjABrTuTZ0HaJx6ZB3SUfn5I_J8eGnbx-P0r4MQ-rA11ukuXJNDas-J7JG2MY6qxzoAZhia2XDpM2Kxti8sswIlXPjLa-FAhrhq8I3kj0hO-2y9c8ILWsQBKdqVXDGayONrw13sqzgXV55l5DZwAvteoxyLJVxrsFXQe5p5J5G7unIvYS82z7xM-Jz_IX2A7J3S4fI2uEGyJvu5U3_S94S8haFQ-P_D11zpk9jgAEikpael6yQUjHGErI3oYT_1k2bB_HSvd7odCFYUWUIwZ-Q19tmfBJj4Vq_vAQamDtE4eFZQp5GadwOCV6uFBd5QuRETidjnra0P74HVHEJSzel4Lv7vUT_6tXNoju96Tan2he4RQAX9P5gIu76ImZvTiY_HU2-VpkexPr5_2DEC3IPexO3w_bIznp16V_CAnFtXwVdcAuxC2CJ
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: Medknow Open Access Journals
  dbid: W3E
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwELaqIiQuCCiPQEFGqkAcQhM7jp1GHBbUqqoEJyp6s2LH2T5oFu2DavvrmbGTsAGJC9f4EXte9tgznwnZS3LGjJUmhqXVxFmuLNhBnsSOFw3sx61TBvOdP3_Jj0-zkzNxtkX6M10fsz-fB5SIABMcCOjTuoKK5pLHgsusXIMsgEvM0rLX5LzsRlsGdVRJGYx6wcpqBdvR5YeTi2pWekAicPTvMMkEBoJ944e9_Raq8I_CDf8Jl5tZmvD94dt7pvIC0wM3FjOP-f-3Zd9Y2v4Mu7x7U7VN1U6h5GaGl-OLKx8bv7HCHT0g97utKZ0EUjwkW659RHYmLbjl12v6hvpgUX8Kv0N-elCPuZt61GpkLq3amuIqGQ4XKXraoCZr6l8hp4vlfHblDmiIOYD1kiKSJtRDIGmK1wc0pIKt6dJH8tI-Z5Nu3LE_JqdHh18_HcfdEw6xBT9xGqfKNjXsGK1IGmEaY42yYEOAxMbIhkuTsKYyaWF4JVSaVc5ktVBQR7iCuUbyJ2S7nbXuGaF5DUJkVa1YxrO6kpWrq8zKvIC-nHI2Ivs9L7Tt8M3xmY3vGvwc5J5G7mnkng7ci8i7ocWPgO3xj7ofkb1DPUTl9h9ARnUnozqVvMktvgYmkqx26M2CoqYIWWdEk0Mnb1E4NNoOGJqtuhQImCCicOlJzpmUinMekd1RTdB5Oy7uxUt3NmehmeCsSBC-PyKvh2JsiXF0rZutoA7QDhF8siQiT4M0DlOCzpXKRBoROZLT0ZzHJe3FuUckl7DtUwr-u9dJ9O9R3U4Xl7eL9aV2qKmIaAijPxiJu74OmZ8j4scbxNcq0b1YP_-fxi_IPRxFOELbJdvL-cq9hE3l0rzyNuAXkC50Xw
  priority: 102
  providerName: Wolters Kluwer Health
Title Neuroregeneration and functional recovery after stroke: advancing neural stem cell therapy toward clinical application
URI http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=1;spage=80;epage=92;aulast=Jiao;type=0
https://www.ncbi.nlm.nih.gov/pubmed/32788451
https://www.proquest.com/docview/2532902906
https://www.proquest.com/docview/2434053740
https://d.wanfangdata.com.cn/periodical/zgsjzsyj-e202101013
https://pubmed.ncbi.nlm.nih.gov/PMC7818886
https://doaj.org/article/173f6c2973504de2828ead14654b5f65
Volume 16
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwELdgCLQXBIyPwJiMNIF4SJfEduzsBRW0aUIaT1TszYodJ7CPdGs7RvfXc-d8rIGJB1SpD_UltX13vjvb9ztCtqM0SYyVJgTTakKeKgvrIItCx7IS_HHrlMF858Mv6cGEfz4SRzfp0e0Ezm8N7bCe1GR2Ovp1sfwACg_-64jHEduJU8lCwSQfJSrNhLhL7oFdkqimh7w_UxAq88Xeeurm0PLWN6yTByyB4JCLeGCvPKz_34v3ivX682bl_au8LvO6gparKZ5_z0_89fcVI7b_iDxsvU86bsTlMbnj6idkY1xD5H22pG-pvw_qN9o3yE-P2zFzlQemRv7RvC4oGsJm_5BiMA2asKS-0DidL2bTE7dLm2sFYBIpgmUCHWJFUzwhoE2215Iu_GVd2qVl0pVj9Kdksr_39dNB2FZpCC2EglUYK1sW4BRaEZXClMYaZWGZgNk2RpZMmigpcxNnhuVCxTx3hhdCAY1wWeJKyZ6RtXpauxeEpgXIiVWFSjjjRS5zV-TcyjSDdznlbEB2Ol5o20KYYyWNUw2hDDJSIyM1MlI3jAzI-_6J8wa-4x-0H5G9PR0Cb_sfprNKt3qsY8nK1GLBLxHxwmHACroYIyqdEWUKL3mHwqFRYKFrNm-zHGCACLSlxykIllSMsYBsDihBre2wuRMv3WmFTgRLsggR-gPypm_GJ_GqXO2ml0ADc4cgPTwKyPNGGvshdUIdEDmQ08GYhy31j-8edFyCZ6cU_O92K9E3vbqu5sfX8-WxdgnuIMAHer87EHd91iR3DiY_XJl8rSLdifXL_-7dK7KOXWi2yDbJ2mJ26V6D07gwW36zZcuvCPD9je39Bu8dauU
linkProvider Scholars Portal
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Neuroregeneration+and+functional+recovery+after+stroke%3A+advancing+neural+stem+cell+therapy+toward+clinical+application&rft.jtitle=Neural+regeneration+research&rft.au=Jiao%2C+Yang&rft.au=Liu%2C+Yu-Wan&rft.au=Chen%2C+Wei-Gong&rft.au=Liu%2C+Jing&rft.date=2021-01-01&rft.pub=Wolters+Kluwer+-+Medknow&rft.issn=1673-5374&rft.eissn=1876-7958&rft.volume=16&rft.issue=1&rft.spage=80&rft.epage=92&rft_id=info:doi/10.4103%2F1673-5374.286955&rft_id=info%3Apmid%2F32788451&rft.externalDocID=PMC7818886
thumbnail_s http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.wanfangdata.com.cn%2Fimages%2FPeriodicalImages%2Fzgsjzsyj-e%2Fzgsjzsyj-e.jpg