Choosing preclinical study models of diabetic retinopathy: key problems for consideration - Mi, Xuesong; Yuan, Ti-Fei; Zhong, Jing-Xiang; Ding, Yong; So, Kwok-Fai (Drug design, development and therapy, 2014)
Keywords: Angiogenesis; animal model; Animal models; Animal models in research; Animals; Culture; Design of experiments; Design optimization; Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 1 - complications; Diabetes Mellitus, Type 2 - complications; Diabetic retinopathy; Diabetic Retinopathy - complications; Diabetic Retinopathy - drug therapy; Disease Models, Animal; Edema; ex vivo culture; Experimental design; Eye surgery; Humans; Hyperglycemia; Hypotheses; in vitro culture; In vivo methods and tests; Medical imaging; Medical research; neurovascular dysfunction; Pathogenesis; Prevention; Researchers; Retina; Retinopathy; Review; Tumor necrosis factor-TNF; Vascular endothelial growth factor; Spain; Hong Kong; China; neurovascular dysfunction; ex vivo culture; animal model; in vitro culture