Hyperresponsiveness of platelets in ischemic stroke

• Published in: Thrombosis and haemostasis Vol. 97; no. 6; p. 974
• Main Authors: Fateh-Moghadam, Suzanne, Htun, Patrik, Tomandl, Bernd, Sander, Dirk, Stellos, Konstantinos, Geisler, Tobias, Langer, Harald, Walton, Kodwo, Handschu, Rene, Garlichs, Christoph, Daniel, Werner G, Gawaz, Meinrad
• Format: Journal Article
• Language: English
• Published: Germany 01.06.2007
• Subjects: Adenosine Diphosphate - metabolism; Adult; Aged; Arachidonic Acid - metabolism; Biomarkers - blood; Blood Platelets - metabolism; Brain Ischemia - blood; Brain Ischemia - complications; Brain Ischemia - mortality; Collagen - metabolism; Epinephrine - metabolism; Female; Follow-Up Studies; Humans; Ischemic Attack, Transient - blood; Ischemic Attack, Transient - diagnosis; Ischemic Attack, Transient - etiology; Ischemic Attack, Transient - mortality; Logistic Models; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Predictive Value of Tests; Recurrence; Risk Assessment; Risk Factors; ROC Curve; Severity of Illness Index; Stroke - blood; Stroke - diagnosis; Stroke - etiology; Stroke - mortality; Time Factors

Platelet activation and aggregation are critical in the pathogenesis of acute ischemic cerebrovascular diseases. The aim of our study was to characterize platelet function in patients with acute ischemic stroke or transient ischemic attack (TIA), and to evaluate the effect of platelet activation on...