Cross-Sectional Associations of Serum Perfluoroalkyl Acids and Thyroid Hormones in U.S. Adults: Variation According to TPOAb and Iodine Status (NHANES 2007–2008)

• Published in: Environmental health perspectives Vol. 124; no. 7; pp. 935 - 942
• Main Authors: Webster, Glenys M., Rauch, Stephen A., Marie, Nathalie Ste, Mattman, Andre, Lanphear, Bruce P., Venners, Scott A.
• Format: Journal Article
• Language: English
• Published: United States National Institute of Environmental Health Sciences 01.07.2016
• Subjects: Adult; Chromatography; Cross-Sectional Studies; Disease susceptibility; Environmental Exposure - analysis; Environmental Exposure - statistics & numerical data; Environmental Pollutants - blood; Female; Fluorocarbons - blood; Health aspects; Health risk assessment; Hormones; Humans; Hyperthyroidism; Hypothyroidism; Iodine; Iodine - blood; Male; Mass spectrometry; Medical research; Medicine, Experimental; Middle Aged; Nutrition Surveys; Organofluorine compounds; Population; Pregnancy; Properties; Scientific imaging; Studies; Sulfonates; Thyroid; Thyroid diseases; Thyroid hormones; Thyroid Hormones - blood; Toxicants; Urine; Womens health; Young Adult; United States; United States > US

Perfluoroalkyl acids (PFASs) are suspected thyroid toxicants, but results from epidemiological studies are inconsistent. We examined associations between serum PFASs and thyroid hormones (THs) in a representative, cross-sectional sample of U.S. adults. We hypothesized that people with high thyroid p...