Increased gut hormones and insulin sensitivity index following a 3-d intervention with a barley kernel-based product: a randomised cross-over study in healthy middle-aged subjects

• Published in: British journal of nutrition Vol. 114; no. 6; pp. 899 - 907
• Main Authors: Nilsson, Anne C., Johansson-Boll, Elin V., Björck, Inger M. E.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 28.09.2015
• Subjects: absorption barrier; Aged; appetite; Appetite Regulation; Barley; Biomarkers - blood; Blood; blood serum; Bread; breads; Breakfast; Carbohydrates; Cohort Studies; Colon - immunology; Colon - metabolism; Colon - microbiology; Cross-Over Studies; digestive system; Elder Nutritional Physiological Phenomena; excretion; experimental design; fasting; Female; Fermentation; gastrointestinal hormones; Gastrointestinal Microbiome - immunology; Glucagon-Like Peptides - blood; Glucagon-Like Peptides - metabolism; Glucose; glycemic control; Health Sciences; hematologic tests; Hordeum - chemistry; Hordeum vulgare; Hormones; Human and Clinical Nutrition; Humans; hydrogen; Hälsovetenskap; Inflammation; Inflammation Mediators - analysis; Inflammation Mediators - blood; Ingestion; Insulin; Insulin Resistance; Intestinal Mucosa - immunology; Intestinal Mucosa - metabolism; Intestinal Mucosa - microbiology; inulin; Male; Medical and Health Sciences; Medicin och hälsovetenskap; Metabolic disorders; Metabolic syndrome; Middle Aged; middle-aged adults; Nutrition and Dietetics; Näringslära; Näringslära och dietkunskap; Obesity; Peptide YY - blood; Peptide YY - metabolism; resistant starch; Triticum aestivum; wheat; whole grain foods; Whole Grains; Glucose tolerance; Barley; Appetite regulation; Gut hormones; Colonic fermentation; Dietary fibre; Dietary prevention; iPeak incremental peak; WWB white wheat bread; BB barley kernel-based bread; GLP glucagon-like peptide; PYY peptide YY; OXM oxyntomodulin; DF dietary fibre; iAUC incremental AUC; RS resistant starch

Certain purified indigestible carbohydrates such as inulin have been shown to stimulate gut-derived hormones involved in glycaemic regulation and appetite regulation, and to counteract systemic inflammation through a gut microbiota-mediated mechanism. Less is known about the properties of indigestib...