Clinical Characteristics and Long-Term Prognosis of Elderly Valvular Heart Disease Patients with Diabetes Mellitus: Five-Year Experience from a Single-Center Study of Southern China

Background. Diabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart disease (VHD) patients is unclear. This study aimed to investigate the effect of DM on the long-term outcome of elderly VHD patients. Methods...

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Published inCardiology research and practice Vol. 2021; pp. 1 - 9
Main Authors Liang, Yuan-Feng, Song, Feier, Liu, Huixia, Liu, Jian, Zhang, Yu-Yuan, Lin, Wei-Dong, Liao, Hong-Tao, Guo, Hui-Ming, Tse, Gary, Liu, Fang-Zhou, Lin, Zhanyi
Format Journal Article
LanguageEnglish
Published United States Hindawi 2021
John Wiley & Sons, Inc
Wiley
Subjects
Cardiac arrhythmia
Cardiovascular disease
Chronic obstructive pulmonary disease
Congenital diseases
Development and progression
Diabetes
Diabetics
Glucose
Heart failure
Heart valve diseases
Hypertension
Ischemia
Kidney diseases
Life expectancy
Medical prognosis
Medical research
Medicine, Experimental
Mortality
Prognosis
Statistical analysis
Stroke (Disease)
Surgery
China
United States > US
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Abstract Background. Diabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart disease (VHD) patients is unclear. This study aimed to investigate the effect of DM on the long-term outcome of elderly VHD patients. Methods. This single-center, observational study enrolled patients aged 65 and older consecutively with confirmed VHD using echocardiography. Patients, divided into the DM group and non-DM group, were followed up for major adverse cardiac and cerebrovascular events (MACCEs), including all-cause death, ischemic stroke, and heart failure rehospitalization. Results. Our study consisted of 532 patients over a median follow-up of 52.9 months. Compared with the non-DM group (n = 377), the DM group (n = 155) had higher incidences of ischemic stroke (25.2% vs. 13.5%, P=0.001), heart failure rehospitalization (37.4% vs. 20.7%, P<0.001), and MACCEs (60.0% vs. 35.8%, P<0.001). After adjustment of confounders by the multivariable cox regression, DM appeared as an independent predictor for MACCEs (adjusted hazard ratio, aHR: 1.88; 95% confidence interval 1.42–2.48; P<0.001). In the subgroup analysis of VHD etiology and functional style, conversely, DM was a protective factor for MACCEs in the patients with rheumatic VHD compared with those without rheumatic VHD (aHR: 0.43 vs. 2.27, P=0.004). Conclusions. DM was an independent predictor for ischemic stroke and heart failure rehospitalization in elderly VHD patients undergoing conservative treatment.
AbstractList Background. Diabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart disease (VHD) patients is unclear. This study aimed to investigate the effect of DM on the long-term outcome of elderly VHD patients. Methods. This single-center, observational study enrolled patients aged 65 and older consecutively with confirmed VHD using echocardiography. Patients, divided into the DM group and non-DM group, were followed up for major adverse cardiac and cerebrovascular events (MACCEs), including all-cause death, ischemic stroke, and heart failure rehospitalization. Results. Our study consisted of 532 patients over a median follow-up of 52.9 months. Compared with the non-DM group (n = 377), the DM group (n = 155) had higher incidences of ischemic stroke (25.2% vs. 13.5%, P=0.001), heart failure rehospitalization (37.4% vs. 20.7%, P<0.001), and MACCEs (60.0% vs. 35.8%, P<0.001). After adjustment of confounders by the multivariable cox regression, DM appeared as an independent predictor for MACCEs (adjusted hazard ratio, aHR: 1.88; 95% confidence interval 1.42–2.48; P<0.001). In the subgroup analysis of VHD etiology and functional style, conversely, DM was a protective factor for MACCEs in the patients with rheumatic VHD compared with those without rheumatic VHD (aHR: 0.43 vs. 2.27, P=0.004). Conclusions. DM was an independent predictor for ischemic stroke and heart failure rehospitalization in elderly VHD patients undergoing conservative treatment.
Diabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart disease (VHD) patients is unclear. This study aimed to investigate the effect of DM on the long-term outcome of elderly VHD patients. This single-center, observational study enrolled patients aged 65 and older consecutively with confirmed VHD using echocardiography. Patients, divided into the DM group and non-DM group, were followed up for major adverse cardiac and cerebrovascular events (MACCEs), including all-cause death, ischemic stroke, and heart failure rehospitalization. Our study consisted of 532 patients over a median follow-up of 52.9 months. Compared with the non-DM group (  = 377), the DM group (  = 155) had higher incidences of ischemic stroke (25.2% vs. 13.5%, =0.001), heart failure rehospitalization (37.4% vs. 20.7%, < 0.001), and MACCEs (60.0% vs. 35.8%, < 0.001). After adjustment of confounders by the multivariable cox regression, DM appeared as an independent predictor for MACCEs (adjusted hazard ratio, aHR: 1.88; 95% confidence interval 1.42-2.48; < 0.001). In the subgroup analysis of VHD etiology and functional style, conversely, DM was a protective factor for MACCEs in the patients with rheumatic VHD compared with those without rheumatic VHD (aHR: 0.43 vs. 2.27, =0.004). DM was an independent predictor for ischemic stroke and heart failure rehospitalization in elderly VHD patients undergoing conservative treatment.
Background. Diabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart disease (VHD) patients is unclear. This study aimed to investigate the effect of DM on the long-term outcome of elderly VHD patients. Methods. This single-center, observational study enrolled patients aged 65 and older consecutively with confirmed VHD using echocardiography. Patients, divided into the DM group and non-DM group, were followed up for major adverse cardiac and cerebrovascular events (MACCEs), including all-cause death, ischemic stroke, and heart failure rehospitalization. Results. Our study consisted of 532 patients over a median follow-up of 52.9 months. Compared with the non-DM group (n = 377), the DM group (n = 155) had higher incidences of ischemic stroke (25.2% vs. 13.5%, P = 0.001 ), heart failure rehospitalization (37.4% vs. 20.7%, P < 0.001 ), and MACCEs (60.0% vs. 35.8%, P < 0.001 ). After adjustment of confounders by the multivariable cox regression, DM appeared as an independent predictor for MACCEs (adjusted hazard ratio, aHR: 1.88; 95% confidence interval 1.42–2.48; P < 0.001 ). In the subgroup analysis of VHD etiology and functional style, conversely, DM was a protective factor for MACCEs in the patients with rheumatic VHD compared with those without rheumatic VHD (aHR: 0.43 vs. 2.27, P = 0.004 ). Conclusions. DM was an independent predictor for ischemic stroke and heart failure rehospitalization in elderly VHD patients undergoing conservative treatment.
Diabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart disease (VHD) patients is unclear. This study aimed to investigate the effect of DM on the long-term outcome of elderly VHD patients.BACKGROUNDDiabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart disease (VHD) patients is unclear. This study aimed to investigate the effect of DM on the long-term outcome of elderly VHD patients.This single-center, observational study enrolled patients aged 65 and older consecutively with confirmed VHD using echocardiography. Patients, divided into the DM group and non-DM group, were followed up for major adverse cardiac and cerebrovascular events (MACCEs), including all-cause death, ischemic stroke, and heart failure rehospitalization.METHODSThis single-center, observational study enrolled patients aged 65 and older consecutively with confirmed VHD using echocardiography. Patients, divided into the DM group and non-DM group, were followed up for major adverse cardiac and cerebrovascular events (MACCEs), including all-cause death, ischemic stroke, and heart failure rehospitalization.Our study consisted of 532 patients over a median follow-up of 52.9 months. Compared with the non-DM group (n = 377), the DM group (n = 155) had higher incidences of ischemic stroke (25.2% vs. 13.5%, P=0.001), heart failure rehospitalization (37.4% vs. 20.7%, P < 0.001), and MACCEs (60.0% vs. 35.8%, P < 0.001). After adjustment of confounders by the multivariable cox regression, DM appeared as an independent predictor for MACCEs (adjusted hazard ratio, aHR: 1.88; 95% confidence interval 1.42-2.48; P < 0.001). In the subgroup analysis of VHD etiology and functional style, conversely, DM was a protective factor for MACCEs in the patients with rheumatic VHD compared with those without rheumatic VHD (aHR: 0.43 vs. 2.27, P=0.004).RESULTSOur study consisted of 532 patients over a median follow-up of 52.9 months. Compared with the non-DM group (n = 377), the DM group (n = 155) had higher incidences of ischemic stroke (25.2% vs. 13.5%, P=0.001), heart failure rehospitalization (37.4% vs. 20.7%, P < 0.001), and MACCEs (60.0% vs. 35.8%, P < 0.001). After adjustment of confounders by the multivariable cox regression, DM appeared as an independent predictor for MACCEs (adjusted hazard ratio, aHR: 1.88; 95% confidence interval 1.42-2.48; P < 0.001). In the subgroup analysis of VHD etiology and functional style, conversely, DM was a protective factor for MACCEs in the patients with rheumatic VHD compared with those without rheumatic VHD (aHR: 0.43 vs. 2.27, P=0.004).DM was an independent predictor for ischemic stroke and heart failure rehospitalization in elderly VHD patients undergoing conservative treatment.CONCLUSIONSDM was an independent predictor for ischemic stroke and heart failure rehospitalization in elderly VHD patients undergoing conservative treatment.
Audience Academic
Author Liang, Yuan-Feng
Tse, Gary
Liu, Fang-Zhou
Lin, Zhanyi
Lin, Wei-Dong
Liu, Huixia
Liu, Jian
Zhang, Yu-Yuan
Song, Feier
Guo, Hui-Ming
Liao, Hong-Tao
AuthorAffiliation 5 Department of Medicine and Therapeutics, Faculty of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong, China
2 Department of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China
3 Department of Cardiac Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China
4 Department of Cardiology, Atrial Fibrillation Center, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China
7 Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles 90048, CA, USA
1 Department of Geriatrics, Guangdong Provincial Geriatrics Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China
6 Li Ka Shing Institute of Health Sciences, Faculty of Medicine, Chinese University
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/34745659$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1093/ejechocard/jen179
10.1161/circulationaha.108.190811
10.1016/s1474-4422(12)70005-4
10.1055/s-2003-37280
10.1016/j.jtcvs.2014.05.014
10.1016/j.jacc.2003.09.037
10.1111/j.2040-1124.2010.00018.x
10.1111/j.1076-7460.2003.00696.x
10.2174/1871530315666150316124019
10.1001/jama.291.14.1720
10.1016/j.ejcts.2009.12.025
10.1016/j.ccl.2004.06.006
10.1016/j.athoracsur.2010.04.066
10.1086/313753
10.1016/j.athoracsur.2010.03.111
10.1016/j.repc.2018.02.012
10.1016/s1474-4422(19)30079-1
10.1016/s2213-8587(19)30405-x
10.1093/eurheartj/ehv134
10.1161/circulationaha.113.005275
10.1186/ar4290
10.1016/j.athoracsur.2010.02.081
10.1136/heart.83.1.116
10.1016/j.bbadis.2019.05.019
10.1016/j.echo.2005.10.005
10.1093/ejechocard/jen303
10.1136/annrheumdis-2014-205216
10.1016/s0894-7317(03)00335-3
10.1161/cir.0000000000000503
10.2217/ahe.13.8
10.1056/NEJMoa1700456
10.1161/01.cir.103.13.1759
10.1056/nejmoa065085
10.1016/j.ejcts.2004.10.041
10.1136/annrheumdis-2015-208476
10.1093/eurheartj/ehw229
10.1001/archsurg.133.8.887
10.1093/eurheartj/ehz486
10.1152/ajpendo.00284.2006
10.1016/s0733-8651(05)70066-7
10.2337/diacare.24.9.1614
10.1186/1749-8090-2-33
10.1161/01.cir.0000053558.55471.2d
10.11909/j.issn.1671-5411.2019.01.007
10.1016/S0140-6736(10)60484-9
10.1111/hex.12393
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References 22
44
23
45
24
46
25
47
26
48
27
International Diabetes Federation (8) 2019
28
29
P. M. Seferovic (39) 2015; 36
J. L. D’Arcy (2) 2017; 37
30
31
32
11
33
12
34
13
35
14
36
15
16
38
17
18
19
F. Cosentino (37) 2020; 41
3
4
5
6
7
World Health Organization (10) 2006
9
40
41
20
42
R. A. Nishimura (1) 2014; 148
21
43
References_xml – ident: 17
  doi: 10.1093/ejechocard/jen179
– ident: 20
  doi: 10.1161/circulationaha.108.190811
– ident: 34
  doi: 10.1016/s1474-4422(12)70005-4
– ident: 42
  doi: 10.1055/s-2003-37280
– volume: 148
  issue: 1
  year: 2014
  ident: 1
  article-title: 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association task force on practice guidelines
  publication-title: The Journal of Thoracic and Cardiovascular Surgery
  doi: 10.1016/j.jtcvs.2014.05.014
– volume-title: IDF Diabetes Atlas
  year: 2019
  ident: 8
– ident: 19
  doi: 10.1016/j.jacc.2003.09.037
– ident: 40
  doi: 10.1111/j.2040-1124.2010.00018.x
– ident: 5
  doi: 10.1111/j.1076-7460.2003.00696.x
– ident: 46
  doi: 10.2174/1871530315666150316124019
– ident: 26
  doi: 10.1001/jama.291.14.1720
– ident: 25
  doi: 10.1016/j.ejcts.2009.12.025
– ident: 21
  doi: 10.1016/j.ccl.2004.06.006
– ident: 24
  doi: 10.1016/j.athoracsur.2010.04.066
– ident: 16
  doi: 10.1086/313753
– ident: 43
  doi: 10.1016/j.athoracsur.2010.03.111
– ident: 31
  doi: 10.1016/j.repc.2018.02.012
– ident: 36
  doi: 10.1016/s1474-4422(19)30079-1
– ident: 35
  doi: 10.1016/s2213-8587(19)30405-x
– volume: 36
  start-page: 1718
  issue: 27
  year: 2015
  ident: 39
  article-title: Clinical diabetic cardiomyopathy: a two-faced disease with restrictive and dilated phenotypes
  publication-title: European Heart Journal
  doi: 10.1093/eurheartj/ehv134
– ident: 32
  doi: 10.1161/circulationaha.113.005275
– ident: 47
  doi: 10.1186/ar4290
– volume-title: Definition and Diagnosis of Diabetes Mellitus and Intermediate and Hyperglycaemia. Report of a WHO/IDF Consultation
  year: 2006
  ident: 10
– ident: 27
  doi: 10.1016/j.athoracsur.2010.02.081
– ident: 4
  doi: 10.1136/heart.83.1.116
– ident: 9
  doi: 10.1016/j.bbadis.2019.05.019
– ident: 11
  doi: 10.1016/j.echo.2005.10.005
– ident: 12
  doi: 10.1093/ejechocard/jen303
– ident: 48
  doi: 10.1136/annrheumdis-2014-205216
– ident: 13
  doi: 10.1016/s0894-7317(03)00335-3
– ident: 3
  doi: 10.1161/cir.0000000000000503
– ident: 29
  doi: 10.2217/ahe.13.8
– ident: 41
  doi: 10.1056/NEJMoa1700456
– ident: 15
  doi: 10.1161/01.cir.103.13.1759
– ident: 18
  doi: 10.1056/nejmoa065085
– ident: 22
  doi: 10.1016/j.ejcts.2004.10.041
– ident: 44
  doi: 10.1136/annrheumdis-2015-208476
– volume: 37
  start-page: 3515
  issue: 47
  year: 2017
  ident: 2
  article-title: Large-scale community echocardiographic screening reveals a major burden of undiagnosed valvular heart disease in older people: the OxVALVE population cohort study
  publication-title: European Heart Journal
  doi: 10.1093/eurheartj/ehw229
– ident: 7
  doi: 10.1001/archsurg.133.8.887
– volume: 41
  start-page: 255
  issue: 2
  year: 2020
  ident: 37
  article-title: 2019 ESC guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD
  publication-title: European Heart Journal
  doi: 10.1093/eurheartj/ehz486
– ident: 45
  doi: 10.1152/ajpendo.00284.2006
– ident: 6
  doi: 10.1016/s0733-8651(05)70066-7
– ident: 38
  doi: 10.2337/diacare.24.9.1614
– ident: 23
  doi: 10.1186/1749-8090-2-33
– ident: 14
  doi: 10.1161/01.cir.0000053558.55471.2d
– ident: 30
  doi: 10.11909/j.issn.1671-5411.2019.01.007
– ident: 33
  doi: 10.1016/S0140-6736(10)60484-9
– ident: 28
  doi: 10.1111/hex.12393
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Snippet Background. Diabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart...
Diabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart disease...
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SubjectTerms Cardiac arrhythmia
Cardiovascular disease
Chronic obstructive pulmonary disease
Congenital diseases
Development and progression
Diabetes
Diabetics
Glucose
Heart failure
Heart valve diseases
Hypertension
Ischemia
Kidney diseases
Life expectancy
Medical prognosis
Medical research
Medicine, Experimental
Mortality
Prognosis
Statistical analysis
Stroke (Disease)
Surgery
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Title Clinical Characteristics and Long-Term Prognosis of Elderly Valvular Heart Disease Patients with Diabetes Mellitus: Five-Year Experience from a Single-Center Study of Southern China
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