Detection of Circulating Tumor DNA in Patients with Thyroid Nodules

• Published in: International journal of endocrinology Vol. 2021; pp. 8909224 - 8
• Main Authors: Patel, Krupal B., Cormier, Nicholas, Fowler, James, Partridge, Allison, Theurer, Julie, Black, Morgan, Pinto, Nicole, Yoo, John, Fung, Kevin, MacNeil, Danielle, Stecho, William, Howlett, Christopher, Brackstone, Muriel, Barrett, John W., Nichols, Anthony
• Format: Journal Article
• Language: English
• Published: Egypt Hindawi 2021; John Wiley & Sons, Inc; Hindawi Limited; Wiley
• Subjects: Acids; Biopsy; Cancer patients; Care and treatment; DNA; Endocrinology; Ethylenediaminetetraacetic acid; Hyperplasia; Mutation; Pathology; Patients; Plasma; Statistical analysis; Surgery; Surveillance; Thyroid cancer; Tumors; Ultrasonic imaging; Maryland

Objective. Detection of circulating tumor DNA (ctDNA) in cancer patients can potentially serve as a noninvasive, sensitive test of disease status. The purpose of this study was to determine the ability to detect BRAF (V600E) mutations in the plasma of patients with thyroid nodules, with the goal of...