Lower availability of midbrain serotonin transporter between healthy subjects with and without a family history of major depressive disorder – a preliminary two-ligand SPECT study - Hsieh, P.C.; Chen, K.C.; Yeh, T.L.; Lee, I.H.; Chen, P.S.; Yao, W.J.; Chiu, N.-T.; Chen, C.-C.; Liao, M.-H.; Yang, Y.K. (European psychiatry, 2014)
Keywords: Adult; Adult and adolescent clinical studies; Biological and medical sciences; Cinanserin - analogs & derivatives; Depression; Depressive Disorder, Major - diagnostic imaging; Depressive Disorder, Major - genetics; Depressive Disorder, Major - metabolism; Dopamine Plasma Membrane Transport Proteins - metabolism; Dopamine transporter; Family - psychology; Family history of major depressive disorder; Female; Healthy Volunteers; Humans; Internal Medicine; Iodine Radioisotopes; Male; Medical sciences; Mesencephalon - diagnostic imaging; Mesencephalon - metabolism; Middle Aged; Miscellaneous; Mood disorders; Neostriatum - diagnostic imaging; Neostriatum - metabolism; Organotechnetium Compounds; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Radiopharmaceuticals; Serotonin Plasma Membrane Transport Proteins - metabolism; Serotonin transporter; SPECT; Tomography, Emission-Computed, Single-Photon; Tropanes; Dopamine transporter; Serotonin transporter; Family history of major depressive disorder; SPECT; Radionuclide study; Mood disorder; Availability; Human; Dopamine; Healthy subject; Central nervous system; Depression; Midbrain; Single photon emission tomography; Catecholamine; Photon; Encephalon; Family story; Neurotransmitter; Comparative study; Carrier protein