Evaluation of an enzyme-linked immunospot assay for the immunodiagnosis of atypical spinal tuberculosis (atypical clinical presentation/atypical radiographic presentation) in China

• Published in: The Brazilian journal of infectious diseases Vol. 17; no. 5; pp. 529 - 537
• Main Authors: Yuan, Kai, Zhong, Zhao-ming, Zhang, Qiang, Xu, Shu-chai, Chen, Jian-ting
• Format: Journal Article
• Language: English
• Published: Brazil Elsevier Editora Ltda 01.09.2013; Contexto; Elsevier; Brazilian Society of Infectious Diseases
• Subjects: Adolescent; Adult; Aged; Atypical spinal tuberculosis; Biopsy; Child; Child, Preschool; China; Diagnosis; Enzyme-Linked Immunospot Assay; Enzymes; Female; Health aspects; Humans; Immunodiagnosis; INFECTIOUS DISEASES; Male; Methods; Middle Aged; Mycobacterium tuberculosis - immunology; Original; Sensitivity and Specificity; Spine; T-SPOT.TB kit; Tuberculosis; Tuberculosis, Spinal - diagnosis; Tuberculosis, Spinal - pathology; Young Adult; China; Enzyme-linked immunospot assay; Diagnosis; Atypical spinal tuberculosis; T-SPOT.TB kit

Atypical spinal tuberculosis (TB) usually presents in a slowly indolent manner with nonspecific clinical presentations making the diagnosis a great challenge for physicians. New technologies for the detection of atypical spinal TB are urgently needed. The aim of this study was to assess the diagnost...