Discriminant analysis of longitudinal cortical thickness changes in Alzheimer's disease using dynamic and network features

• Published in: Neurobiology of aging Vol. 33; no. 2; pp. 427.e15 - 427.e30
• Main Authors: Li, Yang, Wang, Yaping, Wu, Guorong, Shi, Feng, Zhou, Luping, Lin, Weili, Shen, Dinggang
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2012
• Subjects: Aged; Aging - pathology; Alzheimer Disease - pathology; Alzheimer's disease; Brain network; Cerebral Cortex - pathology; Classification; Cortical thickness; Dynamics; Female; Humans; Image Interpretation, Computer-Assisted - methods; Internal Medicine; Longitudinal analysis; Magnetic Resonance Imaging - methods; Male; Mild cognitive impairment; Neurology; Reproducibility of Results; Sensitivity and Specificity; Cortical thickness; Mild cognitive impairment; Dynamics; Classification; Longitudinal analysis; Alzheimer's disease; Brain network

Neuroimage measures from magnetic resonance (MR) imaging, such as cortical thickness, have been playing an increasingly important role in searching for biomarkers of Alzheimer's disease (AD). Recent studies show that, AD, mild cognitive impairment (MCI) and normal control (NC) can be distinguis...