Functional Characterization of Promoter Variants of the Adiponectin Gene Complemented by Epidemiological Data

• Published in: Diabetes (New York, N.Y.) Vol. 58; no. 4; pp. 984 - 991
• Main Authors: Laumen, Helmut, Saningong, Akuma D., Heid, Iris M., Hess, Jochen, Herder, Christian, Claussnitzer, Melina, Baumert, Jens, Lamina, Claudia, Rathmann, Wolfgang, Sedlmeier, Eva-Maria, Klopp, Norman, Thorand, Barbara, Wichmann, H.-Erich, Illig, Thomas, Hauner, Hans
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.04.2009
• Subjects: 3T3 Cells; Adipocytes; Adipocytes - physiology; Adiponectin - blood; Adiponectin - deficiency; Adiponectin - genetics; Adult; Aged; Algorithms; Animals; Binding sites; Biological and medical sciences; Cardiovascular disease; Cell Line; Chromosome Mapping; Cloning, Molecular; Diabetes; Diabetes. Impaired glucose tolerance; DNA Primers; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Experiments; Female; Genetic aspects; Genetic Variation; Haplotypes; Health aspects; Humans; Insulin resistance; Male; Medical sciences; Metabolic syndrome; Mice; Middle Aged; Obesity; Original; Physiological aspects; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Protein hormones; Research design; Risk factors; Single nucleotide polymorphisms; Transcription factors; Transfection; Type 2 diabetes; Germany; Endocrinopathy; Characterization; Promoter; Variant; Gene; Diabetes mellitus; Adipokine; Adiponectin

Functional Characterization of Promoter Variants of the Adiponectin Gene Complemented by Epidemiological Data Helmut Laumen 1 , Akuma D. Saningong 1 , Iris M. Heid 2 , 3 , Jochen Hess 4 , Christian Herder 5 , Melina Claussnitzer 1 , Jens Baumert 2 , Claudia Lamina 2 , Wolfgang Rathmann 6 , Eva-Maria...