Proteomics Analysis of Human Skeletal Muscle Reveals Novel Abnormalities in Obesity and Type 2 Diabetes - Hwang, Hyonson; Bowen, Benjamin P.; Lefort, Natalie; Flynn, Charles R.; De Filippis, Elena A.; Roberts, Christine; Smoke, Christopher C.; Meyer, Christian; Højlund, Kurt; Yi, Zhengping; Mandarino, Lawrence J. (Diabetes (New York, N.Y.), 2010)
Keywords: Adult; Analysis; Biological and medical sciences; Biopsy; Body Mass Index; Chaperonin Containing TCP-1 - genetics; Chaperonins - genetics; Cytoskeletal Proteins - genetics; Diabetes; Diabetes Mellitus, Type 2 - genetics; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Female; Fundamental and applied biological sciences. Psychology; Gene expression; Gene Expression Profiling; Glucose Clamp Technique; Health aspects; Humans; Hypotheses; Insulin resistance; Male; Mass Spectrometry; Medical sciences; Metabolic diseases; Metabolism; Middle Aged; Mitochondria, Muscle - metabolism; Muscle, Skeletal - physiopathology; Muscles; Musculoskeletal system; Obesity; Obesity - genetics; Original; Pathogenesis; Peptide Hydrolases - genetics; Physiological aspects; Proteins; Proteomics; Proteomics - methods; Reference Values; Reproducibility; Research design; Scientific imaging; Skeletal muscle; Striated muscle. Tendons; Type 2 diabetes; Vertebrates: osteoarticular system, musculoskeletal system; Endocrinopathy; Type 2 diabetes; Human; Obesity; Nutrition disorder; Metabolic diseases; Striated muscle; Nutritional status