Associative transcriptomics of traits in the polyploid crop species Brassica napus

• Published in: Nature biotechnology Vol. 30; no. 8; pp. 798 - 802
• Main Authors: HARPER, Andrea L, TRICK, Martin, HIGGINS, Janet, FRASER, Fiona, CLISSOLD, Leah, WELLS, Rachel, HATTORI, Chie, WERNER, Peter, BANCROFT, Ian
• Format: Journal Article
• Language: English
• Published: New York, NY Nature Publishing Group 01.08.2012
• Subjects: Agronomy. Soil science and plant productions; Arabidopsis; Arabidopsis thaliana; Biological and medical sciences; Biomarkers; Biotechnology; Brassica napus; Brassica napus - genetics; Fundamental and applied biological sciences. Psychology; Gene expression; Gene Expression Profiling - methods; Genes; Genetic aspects; Genetic markers; Genetic Markers - genetics; Genetic research; Genetics; Genome-Wide Association Study - methods; Genomes; Genomics; Genomics - methods; Physiological aspects; Plant Proteins - genetics; Polyploidy; Quantitative genetics; Quantitative Trait Loci; Rape (Plant); RNA; Seeds; Single nucleotide polymorphisms; Transcription Factors - genetics; Transcriptome; United Kingdom; Polyploidy; Cruciferae; Transcriptomics; Dicotyledones; Angiospermae; Marker assisted selection; Transcriptome; Brassica napus; Spermatophyta; Molecular marker; Cultivated plant
• ISSN: 1087-0156; 1546-1696
• DOI: 10.1038/nbt.2302

Sequencing a genome and identifying genetic markers lays the groundwork for genome-wide association studies, but can be difficult to achieve for polyploid species. Harper et al. present an approach for performing association studies using genetic maps and markers generated from transcriptome sequencing data alone and apply it to the polyploid crop Brassica napus.