Peanut oral immunotherapy transiently expands circulating Ara h 2–specific B cells with a homologous repertoire in unrelated subjects - Patil, Sarita U.; Ogunniyi, Adebola O.; Calatroni, Agustin; Tadigotla, Vasisht R.; Ruiter, Bert; Ma, Alex; Moon, James; Love, J. Christopher; Shreffler, Wayne G. (Journal of allergy and clinical immunology, 2015)
Keywords: 2S Albumins, Plant - immunology; Administration, Oral; Adolescent; Allergies; Allergy and Immunology; Antibody Formation; antibody repertoire; antigen-specific B cells; Antigens; Antigens, Plant - immunology; Arachis hypogaea; B-Lymphocytes - immunology; Cell Proliferation; Cells, Cultured; Child; Clinical outcomes; Clone Cells; Cloning; Desensitization, Immunologic - methods; Epitopes - immunology; Female; Food allergies; food allergy; Gene amplification; Glycoproteins - immunology; Humans; Immunoglobulin E - immunology; Immunoglobulins; Immunologic Memory; Immunotherapy; Lymphocyte Activation; Male; peanut allergy; Peanut Hypersensitivity - immunology; Peanut Hypersensitivity - therapy; Peanuts; BCR; CDR; peanut allergy; APC; Immunotherapy; PNOIT; antigen-specific B cells; NGS; OIT; food allergy; antibody repertoire; Peanut oral immunotherapy; B-cell receptor; Oral immunotherapy; Next-generation sequencing; Complementarity-determining region; Allophycocyanin