Combined hepatocellular-cholangiocarcinoma in a cow

• Published in: Journal of Veterinary Medical Science Vol. 82; no. 1; pp. 84 - 88
• Main Authors: HONDA, Hidetsugu, KIKU, Yoshio, MIKAMI, Osamu, ISHIKAWA, Yoshiharu, KADOTA, Koichi
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.01.2020; Japan Science and Technology Agency; The Japanese Society of Veterinary Science
• Subjects: cattle; Cell differentiation; Cholangiocarcinoma; combined hepatic carcinoma; Cytokeratin; cytokeratin 18; eosinophilic hyaline globule; Hepatocellular carcinoma; Lymph nodes; Metastases; Pathology; combined hepatic carcinoma; cattle; cytokeratin 18; eosinophilic hyaline globule

We examined a 10-year-old cow in which about half of the liver was displaced by malignant tissue consisting of hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC). Cytokeratin (CK) 18 and 7 were expressed in the latter. Metastasis was present in the hepatic, pancreaticoduodenal and mediastina...